Gene Symbol | ITM2B |
---|---|
Entrez Gene | 9445 |
Alt Symbol | ABRI, BRI, BRI2, BRICD2B, E25B, E3-16, FBD, RDGCA, imBRI2 |
Species | Human |
Gene Type | protein-coding |
Description | integral membrane protein 2B |
Other Description | ABri/ADan amyloid peptide|BRICHOS domain containing 2B|immature BRI2|transmembrane protein BRI |
Swissprots | Q9NYH1 Q96B24 Q5W0A3 Q9Y287 |
Accessions | AAP88930 EAX08788 EAX08789 EAX08790 EAX08791 Q9Y287 AF086918 AAP97148 AF092128 AAD40370 AF136973 AAG49434 AF152462 AAD45280 AF246221 AAF66130 AK000503 BAA91210 AK027411 AK130048 BC000554 AAH00554 BC016148 AAH16148 BC018053 BT006863 AAP35509 DA087198 DQ890591 ABM92208 DQ893759 ABM84685 NM_021999 NP_068839 |
Function | Bri23 peptide prevents aggregation of APP beta-amyloid protein 42 peptide into toxic oligomers. |
Subcellular Location | Bri23 peptide: Secreted. Note=Detected in the cerebral spinal fluid (CSF). |
Tissue Specificity | Ubiquitous. Expressed in brain. |