| Gene Symbol |
TMEM55B
|
| Entrez Gene |
90809
|
| Alt Symbol |
C14orf9
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
transmembrane protein 55B
|
| Other Description |
ptdIns-4,5-P(2) 4-phosphatase type I|ptdIns-4,5-P2 4-Ptase I|type 1 PtdIns-4,5-P2 4-Ptase|type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase
|
| Swissprots |
Q86U09 Q86T03 Q9BU67 Q8WUC0 Q9NSU8 B2RA35
|
| Accessions |
EAW66460 EAW66461 EAW66462 Q86T03 AK314021 BAG36732 AL137727 CAB70896 AM392745 CAL37623 BC002867 AAH02867 BC020947 AAH20947 BX161490 CAD61939 BX248025 CAD62347 CA430067 NM_001100814 NP_001094284 NM_144568 NP_653169
|
| Function |
Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 4,5-bisphosphate. Does not hydrolyze phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4-bisphosphate, inositol 3,5-bisphosphate, inositol 3,4- bisphosphate, phosphatidylinositol 5-monophosphate, phosphatidylinositol 4-monophosphate and phosphatidylinositol 3- monophosphate. {ECO:0000269|PubMed:16365287}.
|
| Subcellular Location |
Late endosome membrane {ECO:0000269|PubMed:16365287}; Multi-pass membrane protein {ECO:0000269|PubMed:16365287}. Lysosome membrane {ECO:0000269|PubMed:16365287}; Multi-pass membrane protein {ECO:0000269|PubMed:16365287}.
|
| Tissue Specificity |
Ubiquitous. {ECO:0000269|PubMed:16365287}.
|