Gene Symbol | Cfd |
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Entrez Gene | 11537 |
Alt Symbol | Adn, DF |
Species | Mouse |
Gene Type | protein-coding |
Description | complement factor D (adipsin) |
Other Description | 28 kDa adipocyte protein|C3 convertase activator|D component (adipsin) of complement|adipsin|complement factor D|properdin factor D |
Swissprots | P03953 Q61280 |
Accessions | AAA37262 CAA28378 CAA28379 EDL31632 EDL31633 EDL31634 EDL31635 P03953 AK143817 BAE25550 BC138778 AAI38779 BC138779 AAI38780 BC145412 AAI45413 BE136302 DV051476 M11768 AAA40486 NM_001291915 NP_001278844 NM_013459 NP_038487 |
Function | Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway. |
Subcellular Location | Secreted. |
Top Pathways | Complement and coagulation cascades, Staphylococcus aureus infection |
Adipsin CRISPR/Cas9 KO Plasmid (m) - sc-419011 from Santa Cruz Biotechnology
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Adipsin HDR Plasmid (m) - sc-419011-HDR from Santa Cruz Biotechnology
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Adipsin Double Nickase Plasmid (m) - sc-419011-NIC from Santa Cruz Biotechnology
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Adipsin Double Nickase Plasmid (m2) - sc-419011-NIC-2 from Santa Cruz Biotechnology
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Adipsin CRISPR Activation Plasmid (m) - sc-419011-ACT from Santa Cruz Biotechnology
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Adipsin CRISPR Activation Plasmid (m2) - sc-419011-ACT-2 from Santa Cruz Biotechnology
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Adipsin Lentiviral Activation Particles (m) - sc-419011-LAC from Santa Cruz Biotechnology
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Adipsin Lentiviral Activation Particles (m2) - sc-419011-LAC-2 from Santa Cruz Biotechnology
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Adipsin siRNA (m) - sc-29647 from Santa Cruz Biotechnology
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Adipsin shRNA Plasmid (m) - sc-29647-SH from Santa Cruz Biotechnology
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Adipsin shRNA (m) Lentiviral Particles - sc-29647-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN28635 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND28635 from Sigma-Aldrich
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CFD siRNA (Mouse) - CRM0081 from Cohesion Biosciences
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CFD - MBS8221132 from MyBioSource
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Adipsin CRISPR/Cas9 KO Plasmid (m2) - sc-419011-KO-2 from Santa Cruz Biotechnology
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Adipsin HDR Plasmid (m2) - sc-419011-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Mouse CFD (NM_013459.2) - SHH262397 from Creative biogene
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Mouse CFD siRNA - orb279557 from Biorbyt
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CFD shRNA Plasmid (Mouse) - CHM0081 from Cohesion Biosciences
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