PPARGC1B

Gene Symbol PPARGC1B
Entrez Gene 133522
Alt Symbol ERRL1, PERC, PGC-1(beta), PGC1B
Species Human
Gene Type protein-coding
Description peroxisome proliferator-activated receptor gamma, coactivator 1 beta
Other Description PGC-1-related estrogen receptor alpha coactivator|PPAR-gamma coactivator 1-beta|PPARGC-1-beta|peroxisome proliferator-activated receptor gamma coactivator 1-beta
Swissprots Q8TDE5 B3KVW0 A2RUN0 Q86YN4 Q8TDE4 A2RUM8 Q86YN6 Q86YN3 Q8N1N9 Q86YN5
Accessions EAW61759 EAW61760 EAW61761 EAW61762 EAW61763 Q86YN6 AF468496 AAL78633 AF468497 AAL78634 AK024346 AK095391 BAC04541 AK123614 BAG53922 AK123715 AY188947 AAO40022 AY188948 AAO40023 AY188949 AAO40024 AY188950 AAO40025 BC026956 AAH26956 BC132971 AAI32972 BC132973 AAI32974 BC144251 AAI44252 BX648997 CA435617 XM_005268372 XP_005268429 XM_011537553 XP_011535855 XM_011537554 XP_011535856 XM_011537555 XP_011535857 XM_011537556 XP_011535858 XM_011537557 XP_011535859 NM_001172698 NP_001166169 NM_001172699 NP_001166170 NM_133263 NP_573570
Function Plays a role of stimulator of transcription factors and nuclear receptors activities. Activates transcritional activity of estrogen receptor alpha, nuclear respiratory factor 1 (NRF1) and glucocorticoid receptor in the presence of glucocorticoids. May play a role in constitutive non-adrenergic-mediated mitochondrial biogenesis as suggested by increased basal oxygen consumption and mitochondrial number when overexpressed. May be involved in fat oxidation and non-oxidative glucose metabolism and in the regulation of energy expenditure. Induces the expression of PERM1 in the skeletal muscle in an ESRRA-dependent manner. {ECO:0000269|PubMed:11854298, ECO:0000269|PubMed:12678921, ECO:0000269|PubMed:15546003, ECO:0000269|PubMed:23836911}.
Subcellular Location Nucleus {ECO:0000269|PubMed:11854298}.
Tissue Specificity Ubiquitous with higher expression in heart, brain and skeletal muscle. {ECO:0000269|PubMed:11854298, ECO:0000269|PubMed:12678921}.

PGC-1β (E-9) - sc-373771 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PGC-1β (E-9): sc-373771. Western blot analysis of PGC-1β expression in Sol8 nuclear extract.

PGC-1β (H-300) - sc-67285 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

PGC-1β (M-142) - sc-67286 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-PGC1 beta antibody - ab118603 from Abcam

Prices $359.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
ab118603 at 3.75 &microg/ml staining PGC1 beta in Human Heart by Immunohistochemistry Formalin-fixed, Paraffin-embedded tissue.

Anti-PGC1 beta antibody - ab98285 from Abcam

Host Rabbit
Clonality Polyclonal
Anti-PGC1 beta antibody (ab98285) at 1 µg/ml + OVCAR-3 cell lysate at 10 µg

Anti-PGC1 beta antibody [EPR12370] - ab176328 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR12370
Western blot analysis on immunoprecipitation pellet from HeLa cell lysate labeling PGC1 beta using ab176328 at a 1/10 dilution.

PGC-1 beta Antibody - NBP1-28722 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PGC-1 beta Antibody [NBP1-28722] - Samples: Whole cell lysate (5, 15 and 50 ug for WB; 1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-PGC-1beta antibody NBP1-28722 used for WB at 0.4 ug/ml (A) and 1 ug/ml (B) and used for IP at 10 ug/mg lysate. PGC-1beta was also immunoprecipitated by rabbit anti-PGC-1beta antibody NBP1-28721, which recognizes an upstream epitope. Detection: Chemiluminescence with exposure times of 30 seconds (A and B).

PGC-1 beta Antibody (6C3F6) - NBP2-37249 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 6C3F6
Western Blot: PGC-1 beta Antibody (6C3F6) [NBP2-37249] - Western blot analysis using PPARGC1B mAb against HEK293 (1) and PPARGC1B (AA: 195-414)-hIgGFc transfected HEK293 (2) cell lysate.

PGC-1 beta Antibody - H00133522-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

Anti-PPARGC1B, (N-terminal) antibody produced in rabbit - SAB2104975 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-PPARGC1B, antibody produced in rabbit: <B>Cat. No. SAB2104975</B>: Immunoblotting analysis of PPARGC1B in OVCAR-3 cell lysate with PPARGC1B anitbody at 1 μg/mL.

Anti-PPARGC1B antibody produced in rabbit - SAB4300858 from Sigma-Aldrich

Prices $230.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PPARGC1B Polyclonal Antibody - A6048 from ABclonal

Prices $220.00, $380.00, $620.00
Sizes 50 µg, 100 µg, 200 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of Mouse heart cell line, using PPARGC1B antibody.

PPARGC1B Antibody - abx004652 from Abbexa

Host Rabbit
Clonality Polyclonal

Anti-PPARGC1B, Polyclonal Antibody - 25-A6048 from ARP American Research Products

Prices $279.00, $549.00
Sizes 50 µg, 200 µg
Host Rabbit
Clonality Polyclonal

PPARGC1B antibody - 22378-1-AP from Proteintech Group

Host Rabbit
Clonality Polyclonal
mouse liver tissue were subjected to SDS PAGE followed by western blot with 22378-1-AP( PPARGC1B Antibody) at dilution of 1:300

PPARGC1B - A6048 from NeoScientific

Prices $380.00, $620.00
Sizes 100 µl, 200 µl
Host Rabbit
Clonality Polyclonal

PPARGC1B Antibody - 37819 from Signalway Antibody

Prices $279.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using #37819 at dilution 1/40.

PGC1-β antibody (pAb) - 39859 from ActiveMotif

Prices $95.00, $410.00
Sizes 10 µl, 100 µl
Host Rabbit
Clonality Polyclonal
PGC1-β antibody tested by Western blot. Western blot of K-562 nuclear extract (40 µg/lane) probed with PGC1-β antibody (pAb) (1: 500 dilution).

Goat Anti-PGC-1beta / PERC Antibody - EB06764 from Everest Biotech

Prices $315.00
Sizes 100µg specific antibody in 200µl
Host Goat
EB06764 (3.8µg/ml) staining of paraffin embedded Human Skeletal Muscle. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

PPARGC1B Antibody - GWB-MN692H from Genway Biotech

Prices $368.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

PPARGC1B Polyclonal Antibody - ESAP13760 from Elabscience

Prices $296.00, $485.00
Sizes 120 μl, 200 μl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of Human prostate cancer using PPARGC1B Polyclonal Antibody at dilution of 1:40

PPARGC1B Polyclonal Antibody - ESAP17069 from Elabscience

Prices $296.00, $485.00
Sizes 120 μl, 200 μl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of Human brain using PPARGC1B Polyclonal Antibody at dilution of 1:30

Anti-PPARGC1B (aa 914-1023) polyclonal antibody - DPAB-DC559 from Creative Diagnostics

Host Mouse
Clonality Polyclonal

Anti-PPARGC1B (aa 2-15) polyclonal antibody - DPABH-10166 from Creative Diagnostics

Host Goat
Clonality Polyclonal

PGC-1beta Antibody - A302-273A from Bethyl Labs

Prices $99.00, $229.00, $339.00
Sizes 20 µl (2 blots), 100 µl (10 blots), 100 µl (1 mg/ml)
Host Rabbit
Clonality Polyclonal
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