Gene Symbol |
Prdx6
|
Entrez Gene |
11758
|
Alt Symbol |
1-Cys Prx, 1-cysPrx, 9430088D19Rik, AA690119, Aop2, Brp-12, CP-3, GPx, Ltw-4, Ltw4, Lvtw-4, NSGPx, ORF06, Prdx5, aiPLA2
|
Species |
Mouse
|
Gene Type |
protein-coding
|
Description |
peroxiredoxin 6
|
Other Description |
1-Cys peroxiredoxin|acidic calcium-independent phospholipase A2|anti-oxidant protein 2, related sequence 3|antioxidant protein 2|non-selenium glutathione peroxidase|peroxiredoxin 5, related sequence 3|peroxiredoxin 6, related sequence 3|peroxiredoxin-6
|
Swissprots |
Q91WT2 Q9QWW0 Q9QWP4 O08709
|
Accessions |
AAC67553 AAD03716 AAP21829 O08709 AF004670 AAC53277 AF093852 AAC63376 AK030413 BAC26952 AK035097 AK076191 BAC36244 AK081980 AK157820 BAE34210 AK161710 BAE36544 AK168223 BAE40177 AK172888 BAD32166 BC013489 AAH13489 BC061181 AAH61181 Y12883 CAA73383 NM_001303408 NP_001290337 NM_007453 NP_031479 NR_130150
|
Function |
Involved in redox regulation of the cell. Can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. May play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury (By similarity). {ECO:0000250}.
|
Subcellular Location |
Cytoplasm {ECO:0000250}. Lysosome {ECO:0000250}. Cytoplasmic vesicle {ECO:0000250}. Note=Also found in lung secretory organelles. {ECO:0000250}.
|
Tissue Specificity |
Highly expressed in heart, kidney and liver. Moderate expression in brain and stomach. Very low levels in intestine.
|
Top Pathways |
Phenylalanine metabolism
|