| Gene Symbol |
KRTAP5-7
|
| Entrez Gene |
440050
|
| Alt Symbol |
KRTAP5-3, KRTAP5.7
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
keratin associated protein 5-7
|
| Other Description |
keratin-associated protein 5-3|keratin-associated protein 5-7|keratin-associated protein 5.3|keratin-associated protein 5.7|ultrahigh sulfur keratin-associated protein 5.7
|
| Swissprots |
B2RNM3 Q6L8G8 Q701N5
|
| Accessions |
Q6L8G8 AB126076 BAD20203 AJ628243 CAF31636 BC136967 AAI36968 BC136968 AAI36969 BC148790 AAI48791 NM_001012503 NP_001012521
|
| Function |
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins.
|
| Tissue Specificity |
Expressed in hair root but not in skin. {ECO:0000269|PubMed:15144888}.
|