Gene Symbol | KRTAP5-7 |
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Entrez Gene | 440050 |
Alt Symbol | KRTAP5-3, KRTAP5.7 |
Species | Human |
Gene Type | protein-coding |
Description | keratin associated protein 5-7 |
Other Description | keratin-associated protein 5-3|keratin-associated protein 5-7|keratin-associated protein 5.3|keratin-associated protein 5.7|ultrahigh sulfur keratin-associated protein 5.7 |
Swissprots | B2RNM3 Q6L8G8 Q701N5 |
Accessions | Q6L8G8 AB126076 BAD20203 AJ628243 CAF31636 BC136967 AAI36968 BC136968 AAI36969 BC148790 AAI48791 NM_001012503 NP_001012521 |
Function | In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins. |
Tissue Specificity | Expressed in hair root but not in skin. {ECO:0000269|PubMed:15144888}. |
KRTAP5-7 CRISPR/Cas9 KO Plasmid (h) - sc-417966 from Santa Cruz Biotechnology
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KRTAP5-7 HDR Plasmid (h) - sc-417966-HDR from Santa Cruz Biotechnology
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KRTAP5-7 Double Nickase Plasmid (h) - sc-417966-NIC from Santa Cruz Biotechnology
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KRTAP5-7 Double Nickase Plasmid (h2) - sc-417966-NIC-2 from Santa Cruz Biotechnology
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KRTAP5-7 CRISPR Activation Plasmid (h) - sc-417966-ACT from Santa Cruz Biotechnology
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KRTAP5-7 CRISPR Activation Plasmid (h2) - sc-417966-ACT-2 from Santa Cruz Biotechnology
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KRTAP5-7 Lentiviral Activation Particles (h) - sc-417966-LAC from Santa Cruz Biotechnology
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KRTAP5-7 Lentiviral Activation Particles (h2) - sc-417966-LAC-2 from Santa Cruz Biotechnology
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KRTAP5-7 siRNA (h) - sc-96833 from Santa Cruz Biotechnology
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KRTAP5-7 shRNA Plasmid (h) - sc-96833-SH from Santa Cruz Biotechnology
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KRTAP5-7 shRNA (h) Lentiviral Particles - sc-96833-V from Santa Cruz Biotechnology
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KRTAP5-3 RNAi - H00387266-R01 from Novus Biologicals
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MISSION® esiRNA - EHU225501 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN11487 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11487 from Sigma-Aldrich
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KRTAP5-7 siRNA (Human) - CRJ8229 from Cohesion Biosciences
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Human KRTAP5-7 siRNA - orb278730 from Biorbyt
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KRTAP5-7 shRNA Plasmid (Human) - CHJ8229 from Cohesion Biosciences
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KRTAP5-7 miRNA 3'UTR clone - MiUTR1H-05527 from Creative biogene
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