| Gene Symbol |
FGD3
|
| Entrez Gene |
89846
|
| Alt Symbol |
ZFYVE5
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
FYVE, RhoGEF and PH domain containing 3
|
| Other Description |
FGD1 family, member 3|FYVE, RhoGEF and PH domain-containing protein 3|faciogenital dysplasia 3|zinc finger FYVE domain-containing protein 5
|
| Swissprots |
Q5JSP0 Q8N5G1 Q7Z7D9 Q4VX84 F8W7P2
|
| Accessions |
EAW62840 EAW62841 EAW62842 EAW62843 EAW62844 EAW62845 EAW62846 EAW62847 Q5JSP0 AK000004 BAA92229 AK225843 AK292676 BAF85365 AK301974 BAG63386 AY211386 AAP20645 BC032429 AAH32429 BC111054 AAI11055 BF509875 BF510761 BX647829 DA493667 DB161711 EU832153 ACE87503 EU832246 ACE86816 XR_242605 NM_001083536 NP_001077005 NM_001286993 NP_001273922 NM_033086 NP_149077
|
| Function |
Promotes the formation of filopodia. May activate CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm {ECO:0000305}. Cytoplasm, cytoskeleton {ECO:0000305}.
|
| Top Pathways |
Regulation of actin cytoskeleton
|