Gene Symbol | FGD3 |
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Entrez Gene | 89846 |
Alt Symbol | ZFYVE5 |
Species | Human |
Gene Type | protein-coding |
Description | FYVE, RhoGEF and PH domain containing 3 |
Other Description | FGD1 family, member 3|FYVE, RhoGEF and PH domain-containing protein 3|faciogenital dysplasia 3|zinc finger FYVE domain-containing protein 5 |
Swissprots | Q5JSP0 Q8N5G1 Q7Z7D9 Q4VX84 F8W7P2 |
Accessions | EAW62840 EAW62841 EAW62842 EAW62843 EAW62844 EAW62845 EAW62846 EAW62847 Q5JSP0 AK000004 BAA92229 AK225843 AK292676 BAF85365 AK301974 BAG63386 AY211386 AAP20645 BC032429 AAH32429 BC111054 AAI11055 BF509875 BF510761 BX647829 DA493667 DB161711 EU832153 ACE87503 EU832246 ACE86816 XR_242605 NM_001083536 NP_001077005 NM_001286993 NP_001273922 NM_033086 NP_149077 |
Function | Promotes the formation of filopodia. May activate CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000305}. Cytoplasm, cytoskeleton {ECO:0000305}. |
Top Pathways | Regulation of actin cytoskeleton |
FGD3 CRISPR/Cas9 KO Plasmid (h) - sc-407854 from Santa Cruz Biotechnology
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FGD3 HDR Plasmid (h) - sc-407854-HDR from Santa Cruz Biotechnology
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FGD3 Double Nickase Plasmid (h) - sc-407854-NIC from Santa Cruz Biotechnology
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FGD3 Double Nickase Plasmid (h2) - sc-407854-NIC-2 from Santa Cruz Biotechnology
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FGD3 CRISPR Activation Plasmid (h) - sc-407854-ACT from Santa Cruz Biotechnology
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FGD3 CRISPR Activation Plasmid (h2) - sc-407854-ACT-2 from Santa Cruz Biotechnology
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FGD3 Lentiviral Activation Particles (h) - sc-407854-LAC from Santa Cruz Biotechnology
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FGD3 Lentiviral Activation Particles (h2) - sc-407854-LAC-2 from Santa Cruz Biotechnology
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FGD3 siRNA (h) - sc-41715 from Santa Cruz Biotechnology
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FGD3 shRNA Plasmid (h) - sc-41715-SH from Santa Cruz Biotechnology
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FGD3 shRNA (h) Lentiviral Particles - sc-41715-V from Santa Cruz Biotechnology
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FGD3 RNAi - H00089846-R01 from Novus Biologicals
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MISSION® esiRNA - EHU074451 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN8641 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8641 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05944 from Sigma-Aldrich
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FGD3 siRNA (Human) - CRJ3866 from Cohesion Biosciences
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FGD3 - MBS8208200 from MyBioSource
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shRNA set against Human FGD3 (NM_033086.2) - SHH294313 from Creative biogene
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shRNA set against Human FGD3(NM_001083536.1) - SHH056531 from Creative biogene
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Human FGD3 siRNA - orb274367 from Biorbyt
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FGD3 shRNA Plasmid (Human) - CHJ3866 from Cohesion Biosciences
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FGD3 miRNA 3'UTR clone - MiUTR1H-03621 from Creative biogene
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FGD3 miRNA 3'UTR clone - MiUTR3H-14929 from Creative biogene
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