ELAVL1

Gene Symbol	ELAVL1
Entrez Gene	1994
Alt Symbol	ELAV1, HUR, Hua, MelG
Species	Human
Gene Type	protein-coding
Description	ELAV like RNA binding protein 1
Other Description	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)|ELAV-like protein 1|Hu antigen R|embryonic lethal, abnormal vision, drosophila, homolog-like 1|hu-antigen R
Swissprots	Q9BTT1 Q53XN6 B4DVB8 Q15717
Accessions	CCA78939 EAW68949 EAW68950 Q15717 AI375368 AK022334 AK096659 AK301013 BAG62630 AL713686 AW139417 BC003376 AAH03376 BM664469 BM696191 BT009793 AAP88795 BU542524 BX647856 EU176230 ABW03681 EU176535 ABW03336 U38175 AAB41913 W37464 XM_011527777 XP_011526079 NM_001419 NP_001410
Function	RNA-binding protein that binds to the 3'-UTR region of mRNAs and increases their stability. Involved in embryonic stem cells (ESCs) differentiation: preferentially binds mRNAs that are not methylated by N6-methyladenosine (m6A), stabilizing them, promoting ESCs differentiation. Binds to poly-U elements and AU- rich elements (AREs) in the 3'-UTR of target mRNAs. Binds avidly to the AU-rich element in FOS and IL3/interleukin-3 mRNAs. In the case of the FOS AU-rich element, binds to a core element of 27 nucleotides that contain AUUUA, AUUUUA, and AUUUUUA motifs. Binds preferentially to the 5'-UUUU[AG]UUU-3' motif in vitro. With ZNF385A, binds the 3'-UTR of p53/TP53 mRNA to control their nuclear export induced by CDKN2A. Hence, may regulate p53/TP53 expression and mediate in part the CDKN2A anti-proliferative activity. May also bind with ZNF385A the CCNB1 mRNA. {ECO:0000269|PubMed:19029303}.
Subcellular Location	Cytoplasm. Nucleus. Note=Translocates into the cytoplasm following phosphorylation by MAPKAPK2.
Tissue Specificity	Ubiquitous.
Top Pathways	AMPK signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Rat ELAVL1 / HUR ELISA Kit (Sandwich ELISA) - LS-F9365 from LifeSpan Bioscience Category ELISA Kit Prices $780.00 Sizes 1 plate Sensitivity 0.066 ng/ml Range 0.156-10 ng/ml

ELAV-like protein 1 (ELAVL1), Human, ELISA Kit - CSB-EL007592HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

ELAVL1 (Human) IP-WB Antibody Pair - H00001994-PW2 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

ELAV (embryonic lethal, abnormal vision, Drosophila) -like 1 (Hu antigen R) , ELISA Kit - MBS919324 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 6.25 pg/ml Range 25 pg/ml-1600 pg/ml.

ELAV Like Protein 1 (ELAVL1), ELISA Kit - MBS2025072 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.114ng/mL. Range 0.313-20ng/mL

ELAV Like Protein 1 (ELAVL1), ELISA Kit - MBS2019259 from MyBioSource Category ELISA Kit Prices $405.00, $605.00, $820.00, $3,375.00, $6,125.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.066ng/mL. Range 0.156-10ng/mL

ELISA Kit for ELAV Like Protein 1 (ELAVL1) - SEJ780Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.114ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA’s were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

ELISA Kit for ELAV Like Protein 1 (ELAVL1) - SEJ780Ra from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.066ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Human ELAV-like protein 1(ELAVL1) ELISA kit - CSB-EL007592HU from Cusabio Category ELISA Kit Sensitivity 6.25 pg/ml Range 25 pg/ml-1600 pg/ml

ELISA Kit for ELAV Like Protein 1 (ELAVL1) - SEJ780Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.114ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA's were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

Human ELAVL1 / HUR ELISA Kit (Sandwich ELISA) - LS-F25560 from LifeSpan Bioscience Category ELISA Kit Prices $780.00 Sizes 1 plate Sensitivity 0.114 ng/ml Range 0.156-10 ng/ml

Human ELAVL1 ELISA Kit - E012899 from Biobool Category ELISA Kit Sensitivity Typically less than 0.114ng/mL.

ELAVL1 ELISA Kit (Human) (OKCD02015) - OKCD02015 from Aviva Systems Biology Category ELISA Kit Prices $545.00 Sizes 96 wells Sensitivity < 0.117 ng/mL Range 0.312 - 20 ng/mL

anti-ELAVL1 / HuR antibody - ARG56587 from Arigo Biolaboratories Category ELISA Kit

ELAV Like Protein 1 (ELAVL1), ELISA Kit - MBS9373881 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ELAVL1 ELISA Kit (Human) (OKCA02096) - OKCA02096 from Aviva Systems Biology Category ELISA Kit Sensitivity 6.25 pg/mL Range 25 pg/mL-1,600 pg/mL

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