| Gene Symbol |
Arpc2
|
| Entrez Gene |
76709
|
| Alt Symbol |
2210023N03Rik, 34kDa, p34-Arc
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
actin related protein 2/3 complex, subunit 2
|
| Other Description |
actin-related protein 2/3 complex subunit 2|arp2/3 complex 34 kDa subunit
|
| Swissprots |
Q3U870 Q9CVB6
|
| Accessions |
EDL00309 Q9CVB6 AK008777 BAB25889 AK037662 AK083263 AK151513 BAE30463 AK152356 BAE31148 AK170061 AK211266 AK213157 AV115645 BC099504 AAH99504 BC115750 AAI15751 BF016986 BY440113 XM_006496317 XP_006496380 NM_029711 NP_083987
|
| Function |
Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm, cytoskeleton {ECO:0000250}. Cell projection {ECO:0000250}. Cell junction, synapse, synaptosome {ECO:0000269|PubMed:24153177}.
|
| Tissue Specificity |
Expressed in hippocampal neurons (at protein level). {ECO:0000269|PubMed:24153177}.
|
| Top Pathways |
Fc gamma R-mediated phagocytosis, Bacterial invasion of epithelial cells, Salmonella infection, Regulation of actin cytoskeleton
|