| Gene Symbol |
SV2C
|
| Entrez Gene |
22987
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
synaptic vesicle glycoprotein 2C
|
| Other Description |
synaptic vesicle protein 2C
|
| Swissprots |
Q496J9 Q9UPU8 Q496K1
|
| Accessions |
CAG34347 EAW95771 EAW95772 Q496J9 AB028977 BAA83006 AK094917 BAG52953 AK094995 BC100824 AAI00825 BC100825 AAI00826 BC100826 AAI00827 BC100827 AAI00828 DA725900 R44558 XM_011543281 XP_011541583 XM_011543282 XP_011541584 NM_001297716 NP_001284645 NM_014979 NP_055794
|
| Function |
Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Enriched in small synaptic vesicles and adrenal microsomes, not present in chromaffin granules. Associated with both insulin granules and synaptic-like microvesicles in insulin-secreting cells of the pancreas (By similarity). {ECO:0000250}.
|
| Top Pathways |
ECM-receptor interaction
|
![Western Blot: SV2C Overexpression Lysate (Adult Normal) [NBP2-07235] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for SV2C.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/18266_SV2C%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBP2-07235-img0001.jpg)