Gene Symbol | SV2C |
---|---|
Entrez Gene | 22987 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | synaptic vesicle glycoprotein 2C |
Other Description | synaptic vesicle protein 2C |
Swissprots | Q496J9 Q9UPU8 Q496K1 |
Accessions | CAG34347 EAW95771 EAW95772 Q496J9 AB028977 BAA83006 AK094917 BAG52953 AK094995 BC100824 AAI00825 BC100825 AAI00826 BC100826 AAI00827 BC100827 AAI00828 DA725900 R44558 XM_011543281 XP_011541583 XM_011543282 XP_011541584 NM_001297716 NP_001284645 NM_014979 NP_055794 |
Function | Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Enriched in small synaptic vesicles and adrenal microsomes, not present in chromaffin granules. Associated with both insulin granules and synaptic-like microvesicles in insulin-secreting cells of the pancreas (By similarity). {ECO:0000250}. |
Top Pathways | ECM-receptor interaction |
SV2C CRISPR/Cas9 KO Plasmid (h) - sc-402877 from Santa Cruz Biotechnology
|
||||||||
SV2C HDR Plasmid (h) - sc-402877-HDR from Santa Cruz Biotechnology
|
||||||||
SV2C Double Nickase Plasmid (h) - sc-402877-NIC from Santa Cruz Biotechnology
|
||||||||
SV2C Double Nickase Plasmid (h2) - sc-402877-NIC-2 from Santa Cruz Biotechnology
|
||||||||
SV2C CRISPR Activation Plasmid (h) - sc-402877-ACT from Santa Cruz Biotechnology
|
||||||||
SV2C CRISPR Activation Plasmid (h2) - sc-402877-ACT-2 from Santa Cruz Biotechnology
|
||||||||
SV2C Lentiviral Activation Particles (h) - sc-402877-LAC from Santa Cruz Biotechnology
|
||||||||
SV2C Lentiviral Activation Particles (h2) - sc-402877-LAC-2 from Santa Cruz Biotechnology
|
||||||||
SV2C siRNA (h) - sc-42279 from Santa Cruz Biotechnology
|
||||||||
SV2C shRNA Plasmid (h) - sc-42279-SH from Santa Cruz Biotechnology
|
||||||||
SV2C shRNA (h) Lentiviral Particles - sc-42279-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU015381 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN20864 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20864 from Sigma-Aldrich
|
||||||||
SV2C siRNA (Human) - CRH7911 from Cohesion Biosciences
|
||||||||
SV2C RNAi - H00022987-R01 from Novus Biologicals
|
||||||||
SV2C - MBS8234024 from MyBioSource
|
||||||||
shRNA set against Human SV2C (NM_014979.1) - SHH421268 from Creative biogene
|
||||||||
shRNA set against Human SV2C(NM_014979.1) - SHL049042 from Creative biogene
|
||||||||
Human SV2C siRNA - orb268413 from Biorbyt
|
||||||||
SV2C shRNA Plasmid (Human) - CHH7911 from Cohesion Biosciences
|
||||||||
SV2C miRNA 3'UTR clone - MiUTR1H-10092 from Creative biogene
|