POLR2G

Gene Symbol	POLR2G
Entrez Gene	5436
Alt Symbol	RPB19, RPB7, hRPB19, hsRPB7
Species	Human
Gene Type	protein-coding
Description	polymerase (RNA) II (DNA directed) polypeptide G
Other Description	DNA directed RNA polymerase II 19 kda polypeptide|DNA-directed RNA polymerase II 19 kDa polypeptide|DNA-directed RNA polymerase II subunit G|DNA-directed RNA polymerase II subunit RPB7|RNA polymerase II 19 kDa subunit|RNA polymerase II seventh subunit|RNA polymerase II subunit B7
Swissprots	B2R5C0 Q2M1Z4 P62487
Accessions	AAB96827 EAW74090 EAW74091 EAW74092 P62487 AK312131 BAG35067 AW016747 BC112162 AAI12163 BC112164 AAI12165 BG530809 U20659 AAA86500 NM_002696 NP_002687
Function	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB7 is part of a subcomplex with RPB4 that binds to a pocket formed by RPB1, RPB2 and RPB6 at the base of the clamp element. The RBP4-RPB7 subcomplex seems to lock the clamp via RPB7 in the closed conformation thus preventing double-stranded DNA to enter the active site cleft. The RPB4-RPB7 subcomplex binds single-stranded DNA and RNA (By similarity). Binds RNA. {ECO:0000250, ECO:0000269|PubMed:9852112}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:9852112}.
Top Pathways	Huntington's disease, Epstein-Barr virus infection, Purine metabolism, RNA polymerase, Pyrimidine metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human POLR2G full length protein - ab159155 from Abcam Category Protein Source Wheat germ Species Human

Human POLR2G protein fragment - ab159156 from Abcam Category Protein Source Wheat germ Species Human

POLR2G / RPB7 Antibody Blocking Peptide - LS-E1690 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

POLR2G / RPB7 Antibody Blocking Peptide - LS-E27130 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

POLR2G Recombinant Protein - H00005436-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human POLR2G Protein - H00005436-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

POLR2G-Antibody-C-term-Blocking-peptide - BP12458b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

POLR2G Protein - GTX108874-pro from GeneTex Category Protein Prices $299.00 Sizes 25 μg Source E. coli Species Human

POLR2G blocking peptide - GTX88361-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Rat, Sheep

POLR2G Peptide - AC21-1949-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

POLR2G - H00005436-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

POLR2G - H00005436-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

POLR2G - H00005436-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

POLR2G - H00005436-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

POLR2G Peptide - 42-776P from ProSci Category Peptide Species Human

POLR2G fusion protein - Ag13370 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

POLR2G fusion protein - ag13338 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human POLR2G, His-tagged - POLR2G-1845H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human DNA-directed RNA polymerase II subunit RPB7(POLR2G) - CSB-YP018334HU CSB-EP018334HU CSB-BP018334HU CSB-MP018334HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

POLR2G Protein - abx163401 from Abbexa Category Protein Species Human, Mouse, Rat

POLR2G, Peptide - MBS426961 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat, Sheep

POLR2G Recombinant Protein Antigen - NBP2-47329PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

POLR2G-Blocking-Peptide-C-term - BP20221b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

POLR2G Peptide, Human - M34GP12095H from Creative Peptides Category Peptide Source Synthetic. Species Human

DNA-directed RNA polymerase II subunit RPB7, Recombinant Protein - MBS1248548 from MyBioSource Category Protein Prices $920.00, $920.00, $1,145.00, $1,145.00, $1,370.00, $1,370.00, $1,825.00, $1,825.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 100 µg (Mammalian-Cell), 1 mg (Yeast) Source E Coli or Yeast or Baculovirus or Mammalian Cell

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