| Gene Symbol |
NPFFR1
|
| Entrez Gene |
64106
|
| Alt Symbol |
GPR147, NPFF1, NPFF1R1, OT7T022
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
neuropeptide FF receptor 1
|
| Other Description |
G protein-coupled receptor 147|G-protein coupled receptor 147|RFamide-related peptide receptor OT7T022|neuropeptide FF 1
|
| Swissprots |
Q8NGR0 A2RRF0 Q96RN3 Q9GZQ6
|
| Accessions |
BAC05950 EAW54387 Q9GZQ6 AB040104 BAB17677 AF268898 AAG41397 AF330055 AAK94199 BC131580 AAI31581 EU432128 ABY87927 NM_022146 NP_071429
|
| Function |
Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
| Top Pathways |
Neuroactive ligand-receptor interaction
|