Gene Symbol | NPFFR1 |
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Entrez Gene | 64106 |
Alt Symbol | GPR147, NPFF1, NPFF1R1, OT7T022 |
Species | Human |
Gene Type | protein-coding |
Description | neuropeptide FF receptor 1 |
Other Description | G protein-coupled receptor 147|G-protein coupled receptor 147|RFamide-related peptide receptor OT7T022|neuropeptide FF 1 |
Swissprots | Q8NGR0 A2RRF0 Q96RN3 Q9GZQ6 |
Accessions | BAC05950 EAW54387 Q9GZQ6 AB040104 BAB17677 AF268898 AAG41397 AF330055 AAK94199 BC131580 AAI31581 EU432128 ABY87927 NM_022146 NP_071429 |
Function | Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Top Pathways | Neuroactive ligand-receptor interaction |
NPFF1 Receptor CRISPR/Cas9 KO Plasmid (h) - sc-408946 from Santa Cruz Biotechnology
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NPFF1 Receptor HDR Plasmid (h) - sc-408946-HDR from Santa Cruz Biotechnology
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NPFF1 Receptor Double Nickase Plasmid (h) - sc-408946-NIC from Santa Cruz Biotechnology
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NPFF1 Receptor Double Nickase Plasmid (h2) - sc-408946-NIC-2 from Santa Cruz Biotechnology
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NPFF1 Receptor CRISPR Activation Plasmid (h) - sc-408946-ACT from Santa Cruz Biotechnology
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NPFF1 Receptor CRISPR Activation Plasmid (h2) - sc-408946-ACT-2 from Santa Cruz Biotechnology
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NPFF1 Receptor Lentiviral Activation Particles (h) - sc-408946-LAC from Santa Cruz Biotechnology
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NPFF1 Receptor Lentiviral Activation Particles (h2) - sc-408946-LAC-2 from Santa Cruz Biotechnology
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NPFF1 Receptor siRNA (h) - sc-45719 from Santa Cruz Biotechnology
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NPFF1 Receptor shRNA Plasmid (h) - sc-45719-SH from Santa Cruz Biotechnology
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NPFF1 Receptor shRNA (h) Lentiviral Particles - sc-45719-V from Santa Cruz Biotechnology
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Neuropeptide FF R1/NPFFR1 RNAi - H00064106-R02 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN15449 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15449 from Sigma-Aldrich
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NPFFR1 siRNA (Human) - CRJ1923 from Cohesion Biosciences
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shRNA set against Human NPFFR1 (NM_022146.4) - SHH354188 from Creative biogene
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Human NPFFR1 siRNA - orb272424 from Biorbyt
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NPFFR1 shRNA Plasmid (Human) - CHJ1923 from Cohesion Biosciences
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NPFFR1 miRNA 3'UTR clone - MiUTR4H-TG06099 from Creative biogene
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