| Gene Symbol |
CHD2
|
| Entrez Gene |
1106
|
| Alt Symbol |
EEOC
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
chromodomain helicase DNA binding protein 2
|
| Other Description |
ATP-dependent helicase CHD2|CHD-2|chromodomain-helicase-DNA-binding protein 2
|
| Swissprots |
O14647 C6G482 Q96IP5
|
| Accessions |
ACS13730 EAX02160 EAX02161 EAX02162 EAX02163 EAX02164 EAX02165 O14647 AA907775 AF006514 AAB87382 AK095933 AK292850 BAF85539 AK295909 BAH12220 AL831836 AY429527 AY429528 BC007347 AAH07347 BC020810 AAH20810 BC047036 BC107885 BC172425 AAI72425 BT007050 AAP35699 BU630151 BX537626 CN277753 CT003638 DB111282 DB121252 DQ088985 AAZ85980 DQ088986 AAZ85981 JF432271 ADZ15488 NM_001042572 NP_001036037 NM_001271 NP_001262
|
| Function |
DNA-binding helicase that specifically binds to the promoter of target genes, leading to chromatin remodeling, possibly by promoting deposition of histone H3.3. Involved in myogenesis via interaction with MYOD1: binds to myogenic gene regulatory sequences and mediates incorporation of histone H3.3 prior to the onset of myogenic gene expression, promoting their expression (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Nucleus {ECO:0000250}. Note=Binds to myogenic gene promoters. {ECO:0000250}.
|