Gene Symbol | CHD2 |
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Entrez Gene | 1106 |
Alt Symbol | EEOC |
Species | Human |
Gene Type | protein-coding |
Description | chromodomain helicase DNA binding protein 2 |
Other Description | ATP-dependent helicase CHD2|CHD-2|chromodomain-helicase-DNA-binding protein 2 |
Swissprots | O14647 C6G482 Q96IP5 |
Accessions | ACS13730 EAX02160 EAX02161 EAX02162 EAX02163 EAX02164 EAX02165 O14647 AA907775 AF006514 AAB87382 AK095933 AK292850 BAF85539 AK295909 BAH12220 AL831836 AY429527 AY429528 BC007347 AAH07347 BC020810 AAH20810 BC047036 BC107885 BC172425 AAI72425 BT007050 AAP35699 BU630151 BX537626 CN277753 CT003638 DB111282 DB121252 DQ088985 AAZ85980 DQ088986 AAZ85981 JF432271 ADZ15488 NM_001042572 NP_001036037 NM_001271 NP_001262 |
Function | DNA-binding helicase that specifically binds to the promoter of target genes, leading to chromatin remodeling, possibly by promoting deposition of histone H3.3. Involved in myogenesis via interaction with MYOD1: binds to myogenic gene regulatory sequences and mediates incorporation of histone H3.3 prior to the onset of myogenic gene expression, promoting their expression (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000250}. Note=Binds to myogenic gene promoters. {ECO:0000250}. |
CHD2 CRISPR/Cas9 KO Plasmid (h) - sc-410727 from Santa Cruz Biotechnology
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CHD2 HDR Plasmid (h) - sc-410727-HDR from Santa Cruz Biotechnology
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CHD2 Double Nickase Plasmid (h) - sc-410727-NIC from Santa Cruz Biotechnology
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CHD2 Double Nickase Plasmid (h2) - sc-410727-NIC-2 from Santa Cruz Biotechnology
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CHD2 CRISPR Activation Plasmid (h) - sc-410727-ACT from Santa Cruz Biotechnology
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CHD2 CRISPR Activation Plasmid (h2) - sc-410727-ACT-2 from Santa Cruz Biotechnology
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CHD2 Lentiviral Activation Particles (h) - sc-410727-LAC from Santa Cruz Biotechnology
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CHD2 Lentiviral Activation Particles (h2) - sc-410727-LAC-2 from Santa Cruz Biotechnology
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CHD2 siRNA (h) - sc-72881 from Santa Cruz Biotechnology
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CHD2 shRNA Plasmid (h) - sc-72881-SH from Santa Cruz Biotechnology
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CHD2 shRNA (h) Lentiviral Particles - sc-72881-V from Santa Cruz Biotechnology
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CHD2 RNAi - H00001106-R01 from Novus Biologicals
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MISSION® esiRNA - EHU043581 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN6042 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6042 from Sigma-Aldrich
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CHD2 siRNA (Human) - CRH0788 from Cohesion Biosciences
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CHD2 - MBS8227136 from MyBioSource
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shRNA set against Human CHD2 (NM_001271.3) - SHH262841 from Creative biogene
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shRNA set against Human CHD2(NM_001042572.2) - SHG173935 from Creative biogene
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Human CHD2 siRNA - orb261290 from Biorbyt
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CHD2 shRNA Plasmid (Human) - CHH0788 from Cohesion Biosciences
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CHD2 miRNA 3'UTR clone - MiUTR1H-02103 from Creative biogene
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CHD2 miRNA 3'UTR clone - MiUTR1H-02104 from Creative biogene
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