AFF2

Gene Symbol AFF2
Entrez Gene 2334
Alt Symbol FMR2, FMR2P, FRAXE, MRX2, OX19
Species Human
Gene Type protein-coding
Description AF4/FMR2 family, member 2
Other Description AF4/FMR2 family member 2|fragile X E mental retardation syndrome protein|fragile X mental retardation 2 protein|protein FMR-2
Swissprots P51816 B7ZLD9 B4DXD5 Q7Z400 A2RTY4 Q7Z2F7 Q14323 B7ZLD6 O43786 O60215 B7WNQ1 Q9UNA5 Q13521 P78407
Accessions AAB71534 BAC80300 BAC80301 BAC80302 BAC80303 BAC80304 BAC80305 BAC80306 BAC80307 BAC80308 BAC80309 BAC80310 BAC80311 BAC80312 BAC80313 BAC80314 BAC80315 BAC80316 BAC80317 BAC80318 BAC80319 EAW61286 EAW61287 EAW61288 EAW61289 P51816 AB102644 BAC81113 AJ001550 CAA04822 AK301927 BAG63347 AK311467 BC132683 AAI32684 BC143740 AAI43741 BC143744 AAI43745 BI030785 L76569 AAA99416 U48436 AAC82513 X95463 CAA64730 NM_001169122 NP_001162593 NM_001169123 NP_001162594 NM_001169124 NP_001162595 NM_001169125 NP_001162596 NM_001170628 NP_001164099 NM_002025 NP_002016
Function RNA-binding protein. Might be involved in alternative splicing regulation through an interaction with G-quartet RNA structure. {ECO:0000269|PubMed:19136466}.
Subcellular Location Nucleus speckle {ECO:0000269|PubMed:19136466}. Note=When splicing is inhibited, accumulates in enlarged speckles.
Tissue Specificity Brain (most abundant in hippocampus and amygdala), placenta and lung.

FMR2 (N-16) - sc-70065 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

FMR2 (T-17) - sc-70068 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
FMR2 (T-17): sc-70068. Immunofluorescence staining of formalin-fixed HeLa cells showing nuclear and cytoplasmic localization. Kindly provided by Yang Xiang, Ph.D., Division of Newborn Medicine, Boston Childrens Hospital, Cell Biology Department, Harvard Medical School.

FMR2 (H-185) - sc-98361 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
FMR2 (H-185): sc-98361. Immunofluorescence staining of formalin-fixed HeLa cells showing nuclear and cytoplasmic localization. Kindly provided by Yang Xiang, Ph.D., Division of Newborn Medicine, Boston Childrens Hospital, Cell Biology Department, Harvard Medical School.

Anti-AFF2 antibody - ab105328 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-AFF2 antibody (ab105328) at 1/500 dilution + Human fetal lung lysate

Anti-AFF2 antibody - ab85450 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-AFF2 antibody (ab85450) at 1 µg/ml (in 5% skim milk / PBS buffer) + human fetal lung lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-AFF2 antibody - ab94564 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-AFF2 antibody (ab94564) at 1 µg/ml (in 5% skim milk / PBS buffer) + OVCAR-3 cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-AFF2 / OX19 Antibody (clone 4D11) - LS-C197238 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4D11
Detection limit for recombinant GST tagged AFF2 is 0.3 ng/ml as a capture antibody.

Anti-AFF2 / OX19 Antibody (aa886-912) - LS-C161016 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
AFF2 Antibody western blot of 293 cell line lysates (35 ug/lane). The AFF2 antibody detected the AFF2 protein (arrow).

Anti-AFF2 / OX19 Antibody (N-Terminus) - LS-C109886 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
AFF2 antibody LS-C109886 Western blot of OVCAR-3 cell lysate.

Anti-AFF2 / OX19 Antibody (aa886-912, APC) - LS-C212619 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AFF2 / OX19 Antibody (aa886-912, AP) - LS-C212617 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AFF2 / OX19 Antibody (aa886-912, Biotin) - LS-C212621 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AFF2 / OX19 Antibody (aa886-912, Azide-free, HRP) - LS-C212623 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AFF2 / OX19 Antibody (aa886-912, PE) - LS-C212624 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AFF2 / OX19 Antibody (aa886-912, FITC) - LS-C212622 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AFF2 / OX19 Antibody (aa885-912) - LS-C319362 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AFF2 / OX19 Antibody (aa1224-1273) - LS-C101676 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
AFF2 antibody LS-C101676 Western blot of Fetal Lung lysate.

AFF2 Antibody - NBP1-81872 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry: AFF2 Antibody [NBP1-81872] - Staining of human cell line U-251MG shows positivity in nucleus and cytoplasm.

AFF2 Antibody (4D11) - H00002334-M08 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4D11

Anti-AFF2, (N-terminal) antibody produced in rabbit - SAB2104197 from Sigma-Aldrich

Prices $346.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-AFF2, antibody produced in rabbit: <B>Cat. No. SAB2104197</B>: Immunoblotting analysis of AFF2 in OVCAR-3 cell lysate with AFF2 anitbody at 1 μg/mL.

Anti-AFF2 antibody produced in rabbit - HPA003139 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-AFF2: <B>Cat. No. HPA003139</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human hippocampus tissue showing cytoplasmic and/or membranous staining of neuronal cells.

Anti-AFF2 antibody produced in rabbit - SAB2100068 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-AFF2: <B>Cat. No.SAB2100068</B>: AFF2 in Fetal Lung tissue lysate with AFF2 antibody at 1.0 μg/mL.

AFF2 antibody - N-terminal region (ARP34260_P050) - ARP34260_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

AFF2 antibody - middle region (ARP38099_P050) - ARP38099_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

AFF2-Antibody-Center - AP18150c from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
AFF2 Antibody (Center) (Cat. #AP18150c) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the AFF2 antibody detected the AFF2 protein (arrow).
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