| Gene Symbol | AFF2 |
|---|---|
| Entrez Gene | 2334 |
| Alt Symbol | FMR2, FMR2P, FRAXE, MRX2, OX19 |
| Species | Human |
| Gene Type | protein-coding |
| Description | AF4/FMR2 family, member 2 |
| Other Description | AF4/FMR2 family member 2|fragile X E mental retardation syndrome protein|fragile X mental retardation 2 protein|protein FMR-2 |
| Swissprots | P51816 B7ZLD9 B4DXD5 Q7Z400 A2RTY4 Q7Z2F7 Q14323 B7ZLD6 O43786 O60215 B7WNQ1 Q9UNA5 Q13521 P78407 |
| Accessions | AAB71534 BAC80300 BAC80301 BAC80302 BAC80303 BAC80304 BAC80305 BAC80306 BAC80307 BAC80308 BAC80309 BAC80310 BAC80311 BAC80312 BAC80313 BAC80314 BAC80315 BAC80316 BAC80317 BAC80318 BAC80319 EAW61286 EAW61287 EAW61288 EAW61289 P51816 AB102644 BAC81113 AJ001550 CAA04822 AK301927 BAG63347 AK311467 BC132683 AAI32684 BC143740 AAI43741 BC143744 AAI43745 BI030785 L76569 AAA99416 U48436 AAC82513 X95463 CAA64730 NM_001169122 NP_001162593 NM_001169123 NP_001162594 NM_001169124 NP_001162595 NM_001169125 NP_001162596 NM_001170628 NP_001164099 NM_002025 NP_002016 |
| Function | RNA-binding protein. Might be involved in alternative splicing regulation through an interaction with G-quartet RNA structure. {ECO:0000269|PubMed:19136466}. |
| Subcellular Location | Nucleus speckle {ECO:0000269|PubMed:19136466}. Note=When splicing is inhibited, accumulates in enlarged speckles. |
| Tissue Specificity | Brain (most abundant in hippocampus and amygdala), placenta and lung. |
Human AFF2 cDNA clone(NM_001170628.1) - CDFH000434 from Creative Biomart
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Human AFF2 cDNA clone(NM_001169123.1) - CDFH000435 from Creative Biomart
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Human AFF2 cDNA clone(NM_001169122.1) - CDFH000436 from Creative Biomart
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Human AFF2 cDNA clone(NM_001169125.1) - CDFH000437 from Creative Biomart
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Human AFF2 cDNA clone(NM_001169124.1) - CDFH000438 from Creative Biomart
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Human AFF2 ORF clone(NM_002025.3) - CDCH015130 from Creative Biomart
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Human AFF2 ORF Clone(NM_001170628.1) - CDCR355799 from Creative Biomart
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Human AFF2 ORF Clone(NM_001170628.1) - CDCR355802 from Creative Biomart
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Human AFF2 ORF Clone(NM_001169122.1) - CDCR355899 from Creative Biomart
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Human AFF2 ORF Clone(NM_001169122.1) - CDCR355900 from Creative Biomart
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Human AFF2 ORF Clone(NM_001169123.1) - CDCR355901 from Creative Biomart
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Human AFF2 ORF Clone(NM_001169123.1) - CDCR355902 from Creative Biomart
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Human AFF2 ORF Clone(NM_001169124.1) - CDCR355904 from Creative Biomart
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Human AFF2 ORF Clone(NM_001169125.1) - CDCR355905 from Creative Biomart
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Human AFF2 ORF Clone(NM_001169125.1) - CDCR355906 from Creative Biomart
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Human AFF2 ORF Clone(NM_001169124.1) - CDCR355909 from Creative Biomart
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Human AFF2 ORF clone(NM_002025.3) - CDCH015130 from Creative biogene
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Human AFF2 ORF Clone(NM_001169125.1) - CDCR355905 from Creative biogene
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Human AFF2 ORF clone (NM_001169123.1) - CDCR025362 from Creative biogene
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Human AFF2 ORF clone (NM_001169122.1) - CDCR025364 from Creative biogene
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Human AFF2 ORF clone (NM_001169124.1) - CDCR025366 from Creative biogene
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Human AFF2 ORF clone (NM_001170628.1) - CDCR025368 from Creative biogene
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Human AFF2 cDNA Clone(NM_001170628.1) - CDFH000434 from Creative biogene
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Human AFF2 cDNA Clone(NM_001169123.1) - CDFH000435 from Creative biogene
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Human AFF2 cDNA Clone(NM_001169122.1) - CDFH000436 from Creative biogene
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