Gene Symbol | EVC2 |
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Entrez Gene | 132884 |
Alt Symbol | LBN |
Species | Human |
Gene Type | protein-coding |
Description | Ellis van Creveld syndrome 2 |
Other Description | ellis-van Creveld syndrome protein 2|limbin |
Swissprots | Q86YT3 Q8NG49 Q86YT4 Q86UK5 |
Accessions | AAY41034 AAY41048 AIV00554 EAW82412 EAW82413 EAW82414 Q86UK5 AB083067 BAC06590 AW137166 AY152402 AAN86577 AY152403 AAN86578 AY185210 AAO22066 BC111455 AAI11456 BC143836 BG755658 XM_011513392 XP_011511694 XM_011513393 XP_011511695 XM_011513394 XP_011511696 NM_001166136 NP_001159608 NM_147127 NP_667338 |
Function | Positive regulator of the hedgehog signaling pathway (By similarity). Plays a critical role in bone formation and skeletal development. {ECO:0000250}. |
Subcellular Location | Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250}. Cell projection, cilium {ECO:0000250}. Cell projection, cilium membrane {ECO:0000250}. Nucleus {ECO:0000250}. |
Tissue Specificity | Found in the heart, placenta, lung, liver, skeletal muscle, kidney and pancreas. {ECO:0000269|PubMed:12468274}. |
Human EVC2 peptide - ab22981 from Abcam
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EVC2 Antibody Blocking Peptide - LS-E25527 from LifeSpan Bioscience
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EVC2 blocking peptide - GTX89863-PEP from GeneTex
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EVC2 Peptide - AC21-0356-P from Abcore
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EVC2 Peptide - 45-555P from ProSci
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Recombinant Human Limbin(EVC2) - CSB-YP769777HU CSB-EP769777HU CSB-BP769777HU CSB-MP769777HU from Cusabio
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EVC2/Limbin, Peptide - MBS426859 from MyBioSource
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EVC2 Recombinant Protein Antigen - NBP2-47467PEP from Novus Biologicals
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EVC2 Peptide, Human - M34GP05112H from Creative Peptides
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EVC2 Recombinant Protein Antigen - NBP2-48889PEP from Novus Biologicals
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EVC2 Immunizing peptide - orb16804 from Biorbyt
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Limbin (EVC2), Recombinant Protein - MBS1395179 from MyBioSource
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