Gene Symbol | ZFP42 |
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Entrez Gene | 132625 |
Alt Symbol | REX-1, REX1, ZNF754, zfp-42 |
Species | Human |
Gene Type | protein-coding |
Description | ZFP42 zinc finger protein |
Other Description | REX1 transcription factor|reduced expression protein 1|zinc finger protein 42 homolog|zinc finger protein 754 |
Swissprots | D3DP65 Q96MM3 Q8WXE2 |
Accessions | CAD33430 EAX04610 EAX04611 EAX04612 Q96MM3 AA641545 AF450454 AAL47167 AK056719 BAB71264 AY429593 AAR07993 BC160056 AAI60056 BE301754 CN420210 XM_011531604 XP_011529906 XM_011531605 XP_011529907 XM_011531606 XP_011529908 XM_011531607 XP_011529909 NM_001304358 NP_001291287 NM_174900 NP_777560 |
Function | Involved in the reprogramming of X-chromosome inactivation during the acquisition of pluripotency. Required for efficient elongation of TSIX, a non-coding RNA antisense to XIST. Binds DXPas34 enhancer within the TSIX promoter. Involved in ES cell self-renewal (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000250}. |
Tissue Specificity | Expressed in kidney, epidermal keratinocytes, prostate epithelial cells, bronchial and small airway lung epithelial cells (at protein level). Expressed in malignant kidney and several carcinoma cell lines (at protein level). Expressed in embryonic stem cells, kidney, epidermal keratinocytes, prostate epithelial cells, bronchial and small airway lung epithelial cells. Expressed in embryonal carcinomas, seminomas, malignant kidney and several carcinoma cell lines. {ECO:0000269|PubMed:12110702, ECO:0000269|PubMed:16344273, ECO:0000269|PubMed:16424014, ECO:0000269|PubMed:16865673}. |
Rex-1 CRISPR/Cas9 KO Plasmid (h) - sc-405230 from Santa Cruz Biotechnology
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Rex-1 HDR Plasmid (h) - sc-405230-HDR from Santa Cruz Biotechnology
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Rex-1 Double Nickase Plasmid (h) - sc-405230-NIC from Santa Cruz Biotechnology
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Rex-1 Double Nickase Plasmid (h2) - sc-405230-NIC-2 from Santa Cruz Biotechnology
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Rex-1 CRISPR Activation Plasmid (h) - sc-405230-ACT from Santa Cruz Biotechnology
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Rex-1 CRISPR Activation Plasmid (h2) - sc-405230-ACT-2 from Santa Cruz Biotechnology
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Rex-1 Lentiviral Activation Particles (h) - sc-405230-LAC from Santa Cruz Biotechnology
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Rex-1 Lentiviral Activation Particles (h2) - sc-405230-LAC-2 from Santa Cruz Biotechnology
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Rex-1 siRNA (h) - sc-61460 from Santa Cruz Biotechnology
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Rex-1 shRNA Plasmid (h) - sc-61460-SH from Santa Cruz Biotechnology
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Rex-1 shRNA (h) Lentiviral Particles - sc-61460-V from Santa Cruz Biotechnology
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Rex-1/ZFP42 RNAi - H00132625-R01 from Novus Biologicals
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MISSION® esiRNA - EHU119661 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN23186 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND23186 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09245 from Sigma-Aldrich
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ZFP42 siRNA (Human) - CRJ5095 from Cohesion Biosciences
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ZFP42 - MBS8235977 from MyBioSource
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shRNA set against Human ZFP42 (NM_174900.3) - SHH451124 from Creative biogene
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shRNA set against Human ZFP42(NM_174900.3) - SHL149308 from Creative biogene
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ZFP42 shRNA Plasmid (Human) - CHJ5095 from Cohesion Biosciences
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ZFP42 miRNA 3'UTR clone - MiUTR1H-11433 from Creative biogene
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