DEPDC5

Gene Symbol DEPDC5
Entrez Gene 9681
Alt Symbol DEP.5, FFEVF
Species Human
Gene Type protein-coding
Description DEP domain containing 5
Other Description DEP domain-containing protein 5
Swissprots O75140 A6H8V6 Q5THZ1 B9EGN9 Q5THZ0 A8MPX9 Q9UGV8 Q6MZX3 Q68DR1 Q6PEZ1 Q5THZ3 Q9UH13 B4DH93 Q5K3V5 Q5THY9
Accessions AAD08635 EAW59996 EAW59997 EAW59998 EAW59999 O75140 AB014545 BAA31620 AJ698950 CAG27889 AJ698951 CAG27890 AJ704764 CAG28924 AK294583 BAG57774 AK294987 BAG58054 AK299886 BAG61733 AK300737 BAH13337 AK309008 AK316364 BAH14735 BC057797 AAH57797 BC136612 AAI36613 BC144291 BC146766 AAI46767 BM145115 BP354669 BX640828 CAE45904 CA310381 CR749304 CAH18159 DA339804 DB381506 XM_005261862 XP_005261919 XM_011530557 XP_011528859 XM_011530558 XP_011528860 XM_011530559 XP_011528861 XM_011530560 XP_011528862 XM_011530561 XP_011528863 XM_011530562 XP_011528864 XM_011530563 XP_011528865 XM_011530564 XP_011528866 XM_011530565 XP_011528867 XM_011530566 XP_011528868 XM_011530567 XP_011528869 XM_011530568 XP_011528870 XM_011530569 XP_011528871 XR_937972 XR_937973 NM_001007188 NP_001007189 NM_001136029 NP_001129501 NM_001242896 NP_001229825 NM_001242897 NP_001229826 NM_014662 NP_055477 NR_110988
Function As a component of the GATOR1 complex, inhibitor of the amino acid-sensing branch of the TORC1 pathway. The GATOR1 complex strongly increases GTP hydrolysis by RRAGA and RRAGB within RRAGC- containing heterodimers, thereby deactivating RRAGs, releasing mTORC1 from lysosomal surface and inhibiting mTORC1 signaling. {ECO:0000269|PubMed:23723238}.
Subcellular Location Cytoplasm, cytosol {ECO:0000250}. Cytoplasm, perinuclear region {ECO:0000250}.
Tissue Specificity Expressed in developing and adult brain. {ECO:0000269|PubMed:23542701}.

DEPDC5 (C-12) - sc-86115 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

DEPDC5 (D-19) - sc-86116 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-DEPDC5 antibody - ab197255 from Abcam

Prices $370.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Anti-DEPDC5 antibody (ab197255) at 1/500 dilution + 7721 lysate

Anti-DEPDC5 antibody - ab185565 from Abcam

Prices $443.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human stomach tissue labeling DEPDC5 with ab185565 at 1/200 dilution.

Anti-DEPDC5 Antibody (aa1404-1432, AP) - LS-C256035 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DEPDC5 Antibody (aa1404-1432, APC) - LS-C256036 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DEPDC5 Antibody (aa1404-1432, Biotin) - LS-C256037 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DEPDC5 Antibody (aa1404-1432, FITC) - LS-C256038 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DEPDC5 Antibody (aa1404-1432, Azide-free, HRP) - LS-C256039 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DEPDC5 Antibody (aa1404-1432, PE) - LS-C256040 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DEPDC5 Antibody (aa1404-1432) IHC-plus™ - LS-B9330 from LifeSpan Bioscience

Prices $395.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Anti-DEPDC5 antibody IHC staining of human lung, alveoli and macrophages. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

DEP Domain Containing 5 Antibody - NBP2-30444 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

DEP Domain Containing 5 Antibody - NBP2-30484 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: DEP Domain Containing 5 Antibody [NBP2-30484] - Staining of human testis shows strong cytoplasmic positivity in cells in seminiferus ducts and Leydig cells.

ANTI-DEPD5 (C-TERM) antibody produced in rabbit - SAB1302644 from Sigma-Aldrich

Prices $326.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-DEPD5 (C-term): <B>Cat. No. SAB1302644 </B>: Western blot analysis of DEPD5 Antibody (C-term) polyclonal antibody pre-incubated in K562 cell line lysate.<BR/><B>Lanes:</B><BR/>1. without blocking peptide<BR/>2. with blocking peptide.

Anti-DEPDC5 antibody produced in rabbit - HPA054969 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-DEPDC5: <B>Cat. No. HPA054969</B>: Immunohistochemical staining of human testis shows strong cytoplasmic positivity in cells in seminiferus ducts and Leydig cells.

Anti-DEPDC5 antibody produced in rabbit - HPA055619 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-DEPDC5: <B>Cat. No. HPA055619</B>: Immunohistochemical staining of human stomach, upper shows moderate cytoplasmic positivity in glandular cells.

DEPD5-Antibody-C-term - AP12010b from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Overlay histogram showing Hela cells stained with AP12010b (green line). The cells were fixed with 2% paraformaldehyde (10 min) and then permeabilized with 90% methanol for 10 min. The cells were then icubated in 2% bovine serum albumin to block non-specific protein-protein interactions followed by the antibody (AP12010b, 1:25 dilution) for 60 min at 37ºC. The secondary antibody used was Goat-Anti-Rabbit IgG, DyLight® 488 Conjugated Highly Cross-Adsorbed(OH191631) at 1/200 dilution for 40 min at 37ºC. Isotype control antibody (blue line) was rabbit IgG (1μg/1x10^6 cells) used under the same conditions. Acquisition of >10, 000 events was performed.

DEPD5 Antibody - C-terminal region (OAAB08254) - OAAB08254 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

Anti -DEPD5, CT (DEPDC5, KIAA0645, DEP domain-containing protein 5) - 034587 from USBiological Life Science

Host Rabbit
Clonality Polyclonal

Anti -DEPD5, CT (DEPDC5, KIAA0645, DEP domain-containing protein 5) (AP) - 034587-AP from USBiological Life Science

Host Rabbit
Clonality Polyclonal

Anti -DEPD5, CT (DEPDC5, KIAA0645, DEP domain-containing protein 5) (APC) - 034587-APC from USBiological Life Science

Host Rabbit
Clonality Polyclonal

Anti -DEPD5, CT (DEPDC5, KIAA0645, DEP domain-containing protein 5) (Azide free) (HRP) - 034587-HRP from USBiological Life Science

Host Rabbit
Clonality Polyclonal

Anti -DEPD5, CT (DEPDC5, KIAA0645, DEP domain-containing protein 5) (Biotin) - 034587-Biotin from USBiological Life Science

Host Rabbit
Clonality Polyclonal

Anti -DEPD5, CT (DEPDC5, KIAA0645, DEP domain-containing protein 5) (FITC) - 034587-FITC from USBiological Life Science

Host Rabbit
Clonality Polyclonal

Anti -DEPD5, CT (DEPDC5, KIAA0645, DEP domain-containing protein 5) (PE) - 034587-PE from USBiological Life Science

Host Rabbit
Clonality Polyclonal
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