| Gene Symbol |
RAP2C
|
| Entrez Gene |
57826
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
RAP2C, member of RAS oncogene family
|
| Other Description |
ras-related protein Rap-2c|small GTPase RAP2C
|
| Swissprots |
Q9Y3L5 B3KWD6 Q9BTS0 Q5H9H9
|
| Accessions |
EAX11782 EAX11783 Q9Y3L5 AK124801 BAG54098 AK310997 AL049685 CAB41256 AL832461 AY298955 AAP55684 BC003403 AAH03403 BC035382 BC051467 BI767215 BX399437 BX647223 CN308919 DB252216 DB535605 EU832115 ACE87465 EU832161 ACE87511 EU832209 ACE86779 EU832255 ACE86825 XM_006724775 XP_006724838 XM_011531376 XP_011529678 XR_430548 NM_001271186 NP_001258115 NM_001271187 NP_001258116 NM_021183 NP_067006 NR_073150
|
| Function |
Small GTP-binding protein which cycles between a GDP- bound inactive and a GTP-bound active form. May play a role in cytoskeletal rearrangements and regulate cell spreading through activation of the effector TNIK. May play a role in SRE-mediated gene transcription. {ECO:0000269|PubMed:17447155}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:17447155}. Recycling endosome membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}; Cytoplasmic side {ECO:0000250}.
|
| Tissue Specificity |
Expressed in liver, skeletal muscle, prostate, uterus, rectum, stomach, and bladder and to a lower extent in brain, kidney, pancreas, and bone marrow. Expressed in mononuclear leukocytes and megakaryocytes. {ECO:0000269|PubMed:16213650, ECO:0000269|PubMed:17447155}.
|
