Gene Symbol | RAP2C |
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Entrez Gene | 57826 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | RAP2C, member of RAS oncogene family |
Other Description | ras-related protein Rap-2c|small GTPase RAP2C |
Swissprots | Q9Y3L5 B3KWD6 Q9BTS0 Q5H9H9 |
Accessions | EAX11782 EAX11783 Q9Y3L5 AK124801 BAG54098 AK310997 AL049685 CAB41256 AL832461 AY298955 AAP55684 BC003403 AAH03403 BC035382 BC051467 BI767215 BX399437 BX647223 CN308919 DB252216 DB535605 EU832115 ACE87465 EU832161 ACE87511 EU832209 ACE86779 EU832255 ACE86825 XM_006724775 XP_006724838 XM_011531376 XP_011529678 XR_430548 NM_001271186 NP_001258115 NM_001271187 NP_001258116 NM_021183 NP_067006 NR_073150 |
Function | Small GTP-binding protein which cycles between a GDP- bound inactive and a GTP-bound active form. May play a role in cytoskeletal rearrangements and regulate cell spreading through activation of the effector TNIK. May play a role in SRE-mediated gene transcription. {ECO:0000269|PubMed:17447155}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:17447155}. Recycling endosome membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}; Cytoplasmic side {ECO:0000250}. |
Tissue Specificity | Expressed in liver, skeletal muscle, prostate, uterus, rectum, stomach, and bladder and to a lower extent in brain, kidney, pancreas, and bone marrow. Expressed in mononuclear leukocytes and megakaryocytes. {ECO:0000269|PubMed:16213650, ECO:0000269|PubMed:17447155}. |
Rap 2C CRISPR/Cas9 KO Plasmid (h) - sc-418217 from Santa Cruz Biotechnology
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Rap 2C HDR Plasmid (h) - sc-418217-HDR from Santa Cruz Biotechnology
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Rap 2C Double Nickase Plasmid (h) - sc-418217-NIC from Santa Cruz Biotechnology
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Rap 2C Double Nickase Plasmid (h2) - sc-418217-NIC-2 from Santa Cruz Biotechnology
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Rap 2C CRISPR Activation Plasmid (h) - sc-418217-ACT from Santa Cruz Biotechnology
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Rap 2C CRISPR Activation Plasmid (h2) - sc-418217-ACT-2 from Santa Cruz Biotechnology
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Rap 2C Lentiviral Activation Particles (h) - sc-418217-LAC from Santa Cruz Biotechnology
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Rap 2C Lentiviral Activation Particles (h2) - sc-418217-LAC-2 from Santa Cruz Biotechnology
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Rap 2C siRNA (h) - sc-106480 from Santa Cruz Biotechnology
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Rap 2C shRNA Plasmid (h) - sc-106480-SH from Santa Cruz Biotechnology
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Rap 2C shRNA (h) Lentiviral Particles - sc-106480-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU160421 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17952 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17952 from Sigma-Aldrich
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RAP2C siRNA (Human) - CRJ1690 from Cohesion Biosciences
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RAP2C - MBS8200712 from MyBioSource
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shRNA set against Human RAP2C (NM_021183.4) - SHH389640 from Creative biogene
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RAP2C shRNA Plasmid (Human) - CHJ1690 from Cohesion Biosciences
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RAP2C miRNA 3'UTR clone - MiUTR4H-TG07320 from Creative biogene
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