IFIT2

Gene Symbol IFIT2
Entrez Gene 3433
Alt Symbol G10P2, GARG-39, IFI-54, IFI-54K, IFI54, IFIT-2, ISG-54 K, ISG-54K, ISG54, P54, cig42
Species Human
Gene Type protein-coding
Description interferon-induced protein with tetratricopeptide repeats 2
Other Description Interferon, alpha-inducible protein (MW 54kD)|interferon-induced 54 kDa protein|interferon-induced protein 54
Swissprots P09913 Q5T767
Accessions AAA59191 CAA30438 EAW50145 P09913 AA143609 AA765174 AF026944 AK300431 BAG62157 AK312831 BC005987 AAH05987 BC032839 AAH32839 DA631671 EB387611 NM_001547 NP_001538
Function IFN-induced antiviral protein which inhibits expression of viral messenger RNAs lacking 2'-O-methylation of the 5' cap. The ribose 2'-O-methylation would provide a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Viruses evolved several ways to evade this restriction system such as encoding their own 2'-O-methylase for their mRNAs or by stealing host cap containing the 2'-O- methylation (cap snatching mechanism). Binds AU-rich viral RNAs, with or without 5' triphosphorylation, RNA-binding is required for antiviral activity. Can promote apoptosis. {ECO:0000269|PubMed:21190939}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:21190939}. Endoplasmic reticulum {ECO:0000269|PubMed:21190939}.

IFIT2 (C-20) - sc-82640 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

IFIT2 (E-15) - sc-82641 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

IFIT2 (F-12) - sc-390724 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
IFIT2 (F-12): sc-390724. Western blot analysis of IFIT2 expression in SCC-25 whole cell lysate.

IFIT2 (H-150) - sc-367014 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-IFIT2 antibody - ab55837 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Ab55837 at 25 &microg/ml staining the mitotic spindle in NIH3T3 cells; visualised with TRITC conjugated goat anti rabbit IgG.

Anti-IFIT2 antibody - ab113112 from Abcam

Prices $378.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab113112 at 1/100 dilution staining IFIT2 in formalin-fixed, paraffin-embedded human fetal liver by Immunohistochemistry

Anti-IFIT2 antibody - ab168407 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-IFIT2 antibody (ab168407) at 1 µg/mlLane 1 : IFIT2 transfected 293T cell line lysateLane 2 : Non-transfected 293T cell line lysate

Anti-IFIT2 antibody - ab83892 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-IFIT2 antibody (ab83892) at 1 µg/ml + Human fetal liver lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-IFIT2 antibody - ab111965 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-IFIT2 antibody - ab138724 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-IFIT2 antibody (ab138724) at 4 µg/mlLane 1 : K562 lysate without immunizing peptideLane 2 : K562 lysate with immunizing peptideLane 3 : RAW lysateSecondaryGoat anti-rabbit Ig HRPdeveloped using the ECL technique

Anti-IFIT2 antibody - N-terminal - ab154487 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-IFIT2 antibody - N-terminal (ab154487) at 1/1000 dilutionLane 1 : A431 whole cell lysateLane 2 : HepG2 whole cell lysateLysates/proteins at 30 µg per lane.

Anti-ISG54 / IFIT2 Antibody (aa307-335, AP) - LS-C259910 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ISG54 / IFIT2 Antibody (aa307-335, APC) - LS-C259911 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ISG54 / IFIT2 Antibody (aa307-335, Biotin) - LS-C259912 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ISG54 / IFIT2 Antibody (aa307-335, FITC) - LS-C259913 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ISG54 / IFIT2 Antibody (aa307-335, Azide-free, HRP) - LS-C259914 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ISG54 / IFIT2 Antibody (aa307-335, PE) - LS-C259915 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ISG54 / IFIT2 Antibody (aa306-335) - LS-C322153 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ISG54 / IFIT2 Antibody - LS-C308386 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-ISG54 / IFIT2 Antibody - LS-C310702 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ISG54 / IFIT2 Antibody (N-Terminus) - LS-C101940 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
IFIT2 antibody LS-C101940 Western blot of Fetal Liver lysate.

Anti-ISG54 / IFIT2 Antibody (aa307-335) - LS-C165124 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
IFIT2 Antibody western blot of 293 cell line lysates (35 ug/lane). The IFIT2 antibody detected the IFIT2 protein (arrow).

Anti-ISG54 / IFIT2 Antibody (aa100-321) - LS-C178590 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

IFIT2 Antibody - NBP2-15180 from Novus Biologicals

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: IFIT2 Antibody [NBP2-15180] - Analysis of IFIT2 in human K562 lysate in the 1) absence and 2) presence of immunizing peptide, and 3) mouse RAW lysate probed with 4 ug/ml of IFIT2 antibody. Goat anti-rabbit Ig HRP secondary antibody and PicoTect ECL substrate solution were used for this test.

IFIT2 Antibody - NBP1-31164 from Novus Biologicals

Prices $349.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: IFIT2 Antibody [NBP1-31164] - Sample(30 ug of whole cell lysate)A:A431 B:Hep G2 7.5% SDS PAGE, antibody diluted at 1:1000.
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