IFIT2

Gene Symbol	IFIT2
Entrez Gene	3433
Alt Symbol	G10P2, GARG-39, IFI-54, IFI-54K, IFI54, IFIT-2, ISG-54 K, ISG-54K, ISG54, P54, cig42
Species	Human
Gene Type	protein-coding
Description	interferon-induced protein with tetratricopeptide repeats 2
Other Description	Interferon, alpha-inducible protein (MW 54kD)|interferon-induced 54 kDa protein|interferon-induced protein 54
Swissprots	P09913 Q5T767
Accessions	AAA59191 CAA30438 EAW50145 P09913 AA143609 AA765174 AF026944 AK300431 BAG62157 AK312831 BC005987 AAH05987 BC032839 AAH32839 DA631671 EB387611 NM_001547 NP_001538
Function	IFN-induced antiviral protein which inhibits expression of viral messenger RNAs lacking 2'-O-methylation of the 5' cap. The ribose 2'-O-methylation would provide a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Viruses evolved several ways to evade this restriction system such as encoding their own 2'-O-methylase for their mRNAs or by stealing host cap containing the 2'-O- methylation (cap snatching mechanism). Binds AU-rich viral RNAs, with or without 5' triphosphorylation, RNA-binding is required for antiviral activity. Can promote apoptosis. {ECO:0000269|PubMed:21190939}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:21190939}. Endoplasmic reticulum {ECO:0000269|PubMed:21190939}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human IFIT2 full length protein - ab132593 from Abcam Category Protein Source Wheat germ Species Human

Human IFIT2 protein fragment - ab126008 from Abcam Category Protein Source E. coli Species Human

ISG54 / IFIT2 Antibody Blocking Peptide - LS-E4730 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human IFIT2 Protein - H00003433-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

IFIT2-Antibody-Center-Blocking-Peptide - BP17102c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

IFIT2 Blocking Peptide - 33R-8396 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

IFI54 / IFIT2 - H00003433-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

IFI54 / IFIT2 - H00003433-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

IFIT2 fusion protein - ag3283 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human Interferon-induced protein with tetratricopeptide repeats 2(IFIT2) - CSB-YP011021HU CSB-EP011021HU CSB-BP011021HU CSB-MP011021HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

IFI54 / IFIT2 - TP305582 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

IFIT2 Recombinant Protein Antigen - NBP1-85617PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

IFIT2 Peptide, Human - M34GP07427H from Creative Peptides Category Peptide Source Synthetic. Species Human

Interferon-induced protein with tetratricopeptide repeats 2 (IFIT2), Recombinant Protein - MBS961156 from MyBioSource Category Protein Prices $1,255.00, $1,255.00, $1,475.00, $1,475.00, $2,045.00, $2,045.00, $2,510.00, $2,510.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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