Gene Symbol | ARHGAP44 |
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Entrez Gene | 9912 |
Alt Symbol | NPC-A-10, RICH2 |
Species | Human |
Gene Type | protein-coding |
Description | Rho GTPase activating protein 44 |
Other Description | RICH-2|Rho-type GTPase-activating protein RICH2|RhoGAP interacting with CIP4 homologs protein 2|rho GTPase-activating protein 44|rho GTPase-activating protein RICH2 |
Swissprots | Q9Y4Q4 A6NCP5 O75160 A8MQB2 Q7Z5Z7 Q17R89 |
Accessions | EAW89965 EAW89966 EAW89967 EAW89968 EAW89969 Q17R89 AB014572 BAA31647 AK023797 AK294538 BAG57745 AL080100 CAH10728 AL096728 CAB46376 AY320403 AAP73805 BC022452 AAH22452 BC070074 BC094754 BC117412 AAI17413 BC117416 AAI17417 BC143852 BC143853 AAI43854 BC143855 BC143856 BM993036 DA403021 DB461035 XM_005256888 XP_005256945 XM_005256889 XP_005256946 XM_005256890 XP_005256947 XM_005256891 XP_005256948 XM_006721615 XP_006721678 NM_014859 NP_055674 |
Function | GTPase-activating protein (GAP) that stimulates the GTPase activity of Rho-type GTPases. Thereby, controls Rho-type GTPases cycling between their active GTP-bound and inactive GDP- bound states. May act as a GAP for CDC42 and RAC1. Endosomal recycling protein which, in association with SHANK3, is involved in synaptic plasticity. Promotes GRIA1 exocytosis from recycling endosomes and spine morphological changes associated to long-term potentiation. {ECO:0000269|PubMed:11431473}. |
Subcellular Location | Cell projection, dendritic spine {ECO:0000250}. Recycling endosome {ECO:0000250}. Cell junction, synapse {ECO:0000250}. Note=In CA1 hippocampal synapses, detected at both presynaptic and postsynaptic sites. {ECO:0000250}. |
Tissue Specificity | Highly expressed in brain. Expressed at weak level in other tissues. {ECO:0000269|PubMed:11431473}. |
RICH2 (A-7) - sc-390609 from Santa Cruz Biotechnology
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RICH2 (P-15) - sc-165364 from Santa Cruz Biotechnology
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RICH2 (S-16) - sc-165365 from Santa Cruz Biotechnology
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Anti-RICH2 antibody - ab93627 from Abcam
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Anti-ARHGAP44 Antibody (aa784-811, AP) - LS-C268254 from LifeSpan Bioscience
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Anti-ARHGAP44 Antibody (aa784-811, Biotin) - LS-C268255 from LifeSpan Bioscience
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Anti-ARHGAP44 Antibody (aa784-811, APC) - LS-C268253 from LifeSpan Bioscience
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Anti-ARHGAP44 Antibody (aa784-811, FITC) - LS-C268256 from LifeSpan Bioscience
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Anti-ARHGAP44 Antibody (aa784-811, Azide-free, HRP) - LS-C268257 from LifeSpan Bioscience
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Anti-ARHGAP44 Antibody (aa791-819) - LS-C324680 from LifeSpan Bioscience
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Anti-ARHGAP44 Antibody (aa784-811, PE) - LS-C268259 from LifeSpan Bioscience
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Anti-ARHGAP44 Antibody (aa784-811) - LS-C162604 from LifeSpan Bioscience
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ARHGAP44 Antibody - NBP1-93624 from Novus Biologicals
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Anti-ARHGAP44 antibody produced in rabbit - HPA038814 from Sigma-Aldrich
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RICH2 Antibody - C-terminal region (OAAB00673) - OAAB00673 from Aviva Systems Biology
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RICH2-Antibody-C-term - AP10656b from Abgent, a WuXi AppTec company
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ARHGAP44 Polyclonal Antibody - A7357 from ABclonal
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RICH2 (N-term) antibody - AP09868PU-N from Acris Antibodies
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RICH2 (C-term) antibody - AP53665PU-N from Acris Antibodies
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RICH2 antibody - H00009912-B01P from Acris Antibodies
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Anti-ARHGAP44 antibody - STJ29496 from St John's Laboratory Ltd
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ARHGAP44, Polyclonal Antibody - MBS9125539 from MyBioSource
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ARHGAP44 Polyclonal Antibody - EAP2344 from Elabscience
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RICH2 Polyclonal Antibody - PA5-24152 from Thermo Fisher Scientific
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RICH2, Polyclonal Antibody - MBS6003834 from MyBioSource
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