Gene Symbol |
GUCA2B
|
Entrez Gene |
2981
|
Alt Symbol |
GCAP-II, UGN
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
guanylate cyclase activator 2B (uroguanylin)
|
Other Description |
guanylate cyclase activator 2B|prepro-uroguanylin|uroguanylin
|
Swissprots |
Q16661 Q52LV0
|
Accessions |
AAC51729 CAA94311 EAX07169 Q16661 BC069301 AAH69301 BC093779 AAH93779 BC093781 AAH93781 U34279 AAC50416 Z50753 CAA90629 NM_007102 NP_009033
|
Function |
Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins. May be a potent physiological regulator of intestinal fluid and electrolyte transport. May be an autocrine/paracrine regulator of intestinal salt and water transport.
|
Subcellular Location |
Secreted.
|
Tissue Specificity |
Stomach and intestine.
|