Gene Symbol |
ARL4A
|
Entrez Gene |
10124
|
Alt Symbol |
ARL4
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
ADP-ribosylation factor-like 4A
|
Other Description |
ADP-ribosylation factor-like 4|ADP-ribosylation factor-like protein 4A
|
Swissprots |
A4D119 P80418 Q49AF5 P40617
|
Accessions |
EAL24295 EAW93650 EAW93651 EAW93652 P40617 AF493890 AAM12604 AK313233 BAG36044 AU076407 AW022162 AW079064 BC001111 AAH01111 BC003027 AAH03027 BC039123 BI828864 BM550177 BQ948724 BU786406 CD049640 DB451189 DB472672 U73960 AAB39713 NM_001037164 NP_001032241 NM_001195396 NP_001182325 NM_005738 NP_005729 NM_212460 NP_997625
|
Function |
Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Recruits CYTH1, CYTH2, CYTH3 and CYTH4 to the plasma membrane in GDP-bound form. {ECO:0000269|PubMed:10980193, ECO:0000269|PubMed:17398095}.
|
Subcellular Location |
Cell membrane. Cytoplasm. Nucleus, nucleolus. Note=Localization in the nucleolus is dependent by nucleotide binding.
|