Gene Symbol | ARL4A |
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Entrez Gene | 10124 |
Alt Symbol | ARL4 |
Species | Human |
Gene Type | protein-coding |
Description | ADP-ribosylation factor-like 4A |
Other Description | ADP-ribosylation factor-like 4|ADP-ribosylation factor-like protein 4A |
Swissprots | A4D119 P80418 Q49AF5 P40617 |
Accessions | EAL24295 EAW93650 EAW93651 EAW93652 P40617 AF493890 AAM12604 AK313233 BAG36044 AU076407 AW022162 AW079064 BC001111 AAH01111 BC003027 AAH03027 BC039123 BI828864 BM550177 BQ948724 BU786406 CD049640 DB451189 DB472672 U73960 AAB39713 NM_001037164 NP_001032241 NM_001195396 NP_001182325 NM_005738 NP_005729 NM_212460 NP_997625 |
Function | Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Recruits CYTH1, CYTH2, CYTH3 and CYTH4 to the plasma membrane in GDP-bound form. {ECO:0000269|PubMed:10980193, ECO:0000269|PubMed:17398095}. |
Subcellular Location | Cell membrane. Cytoplasm. Nucleus, nucleolus. Note=Localization in the nucleolus is dependent by nucleotide binding. |
ARL4 CRISPR/Cas9 KO Plasmid (h) - sc-418265 from Santa Cruz Biotechnology
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ARL4 HDR Plasmid (h) - sc-418265-HDR from Santa Cruz Biotechnology
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ARL4 Double Nickase Plasmid (h) - sc-418265-NIC from Santa Cruz Biotechnology
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ARL4 Double Nickase Plasmid (h2) - sc-418265-NIC-2 from Santa Cruz Biotechnology
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ARL4 CRISPR Activation Plasmid (h) - sc-418265-ACT from Santa Cruz Biotechnology
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ARL4 CRISPR Activation Plasmid (h2) - sc-418265-ACT-2 from Santa Cruz Biotechnology
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ARL4 Lentiviral Activation Particles (h) - sc-418265-LAC from Santa Cruz Biotechnology
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ARL4 Lentiviral Activation Particles (h2) - sc-418265-LAC-2 from Santa Cruz Biotechnology
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ARL4 siRNA (h) - sc-61992 from Santa Cruz Biotechnology
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ARL4 shRNA Plasmid (h) - sc-61992-SH from Santa Cruz Biotechnology
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ARL4 shRNA (h) Lentiviral Particles - sc-61992-V from Santa Cruz Biotechnology
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ARL4 RNAi - H00010124-R01 from Novus Biologicals
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MISSION® esiRNA - EHU113651 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3490 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3490 from Sigma-Aldrich
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ARL4A siRNA (Human) - CRH6826 from Cohesion Biosciences
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ARL4 RNAi - H00010124-R02 from Novus Biologicals
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ARL4 RNAi - H00010124-R03 from Novus Biologicals
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ARL4A - MBS827049 from MyBioSource
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ARL4A shRNA Plasmid (Human) - CHH6826 from Cohesion Biosciences
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ARL4A miRNA 3'UTR clone - MiUTR4H-TG10605 from Creative biogene
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