| Gene Symbol |
RILPL1
|
| Entrez Gene |
353116
|
| Alt Symbol |
GOSPEL, RLP1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
Rab interacting lysosomal protein-like 1
|
| Other Description |
RILP-like protein 1|rab-interacting lysosomal-like protein 1
|
| Swissprots |
Q8N1M0 Q66K36 Q5EBL4
|
| Accessions |
EAW98415 EAW98416 Q5EBL4 AK096697 BAC04845 AK097550 BC041375 BC080626 AAH80626 BC089444 AAH89444 BX281699 BX359997 XM_005253570 XP_005253627 XM_006719372 XP_006719435 XM_006719373 XP_006719436 XM_006719374 XP_006719437 XM_011538282 XP_011536584 XM_011538283 XP_011536585 XM_011538284 XP_011536586 XM_011538285 XP_011536587 XR_944537 NM_178314 NP_847884
|
| Function |
Plays a role in the regulation of cell shape and polarity. Plays a role in cellular protein transport, including protein transport away from primary cilia. Neuroprotective protein, which acts by sequestring GAPDH in the cytosol and prevent the apoptotic function of GAPDH in the nucleus. Competes with SIAH1 for binding GAPDH (By similarity). Does not regulate lysosomal morphology and distribution. {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm, cytosol {ECO:0000269|PubMed:14668488}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}. Cell projection, cilium {ECO:0000250}.
|
| Tissue Specificity |
Widely expressed. Expressed at lower level in liver and kidney. {ECO:0000269|PubMed:14668488}.
|
