Gene Symbol | RILPL1 |
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Entrez Gene | 353116 |
Alt Symbol | GOSPEL, RLP1 |
Species | Human |
Gene Type | protein-coding |
Description | Rab interacting lysosomal protein-like 1 |
Other Description | RILP-like protein 1|rab-interacting lysosomal-like protein 1 |
Swissprots | Q8N1M0 Q66K36 Q5EBL4 |
Accessions | EAW98415 EAW98416 Q5EBL4 AK096697 BAC04845 AK097550 BC041375 BC080626 AAH80626 BC089444 AAH89444 BX281699 BX359997 XM_005253570 XP_005253627 XM_006719372 XP_006719435 XM_006719373 XP_006719436 XM_006719374 XP_006719437 XM_011538282 XP_011536584 XM_011538283 XP_011536585 XM_011538284 XP_011536586 XM_011538285 XP_011536587 XR_944537 NM_178314 NP_847884 |
Function | Plays a role in the regulation of cell shape and polarity. Plays a role in cellular protein transport, including protein transport away from primary cilia. Neuroprotective protein, which acts by sequestring GAPDH in the cytosol and prevent the apoptotic function of GAPDH in the nucleus. Competes with SIAH1 for binding GAPDH (By similarity). Does not regulate lysosomal morphology and distribution. {ECO:0000250}. |
Subcellular Location | Cytoplasm, cytosol {ECO:0000269|PubMed:14668488}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}. Cell projection, cilium {ECO:0000250}. |
Tissue Specificity | Widely expressed. Expressed at lower level in liver and kidney. {ECO:0000269|PubMed:14668488}. |
RILPL1 CRISPR/Cas9 KO Plasmid (h) - sc-415661 from Santa Cruz Biotechnology
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RILPL1 HDR Plasmid (h) - sc-415661-HDR from Santa Cruz Biotechnology
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RILPL1 Double Nickase Plasmid (h) - sc-415661-NIC from Santa Cruz Biotechnology
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RILPL1 Double Nickase Plasmid (h2) - sc-415661-NIC-2 from Santa Cruz Biotechnology
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RILPL1 CRISPR Activation Plasmid (h) - sc-415661-ACT from Santa Cruz Biotechnology
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RILPL1 CRISPR Activation Plasmid (h2) - sc-415661-ACT-2 from Santa Cruz Biotechnology
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RILPL1 Lentiviral Activation Particles (h) - sc-415661-LAC from Santa Cruz Biotechnology
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RILPL1 Lentiviral Activation Particles (h2) - sc-415661-LAC-2 from Santa Cruz Biotechnology
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RILPL1 siRNA (h) - sc-96169 from Santa Cruz Biotechnology
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RILPL1 shRNA Plasmid (h) - sc-96169-SH from Santa Cruz Biotechnology
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RILPL1 shRNA (h) Lentiviral Particles - sc-96169-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU024401 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN18278 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18278 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07353 from Sigma-Aldrich
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RILPL1 siRNA (Human) - CRJ7560 from Cohesion Biosciences
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RILPL1 - MBS8214955 from MyBioSource
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shRNA set against Human RILPL1 (NM_178314.3) - SHH395756 from Creative biogene
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RILPL1 shRNA Plasmid (Human) - CHJ7560 from Cohesion Biosciences
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RILPL1 miRNA 3'UTR clone - MiUTR3H-13128 from Creative biogene
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