| Gene Symbol |
CCNE2
|
| Entrez Gene |
9134
|
| Alt Symbol |
CYCE2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
cyclin E2
|
| Other Description |
G1/S-specific cyclin-E2
|
| Swissprots |
O95439 O96020
|
| Accessions |
AAV97813 EAW91727 EAW91728 EAW91729 EAW91730 EAW91731 EAW91732 O96020 AA830205 AF091433 AAC80528 AF102778 AAC78145 AF106690 AAD08816 AF112857 AAD08819 BC007015 AAH07015 BC020729 AAH20729 BG720611 BJ990268 DB547256 DQ893494 ABM84420 DQ896366 ABM87365 XM_011517364 XP_011515666 XM_011517365 XP_011515667 XM_011517366 XP_011515668 NM_057749 NP_477097 NM_004702 NM_057735
|
| Function |
Essential for the control of the cell cycle at the late G1 and early S phase.
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:9840943}.
|
| Tissue Specificity |
According to PubMed:9858585, highest levels of expression in adult testis, thymus and brain. Lower levels in placenta, spleen and colon. Consistently elevated levels in tumor- derived cells compared to non-transformed proliferating cells. According to PubMed:9840927: low levels in thymus, prostate, brain, skeletal muscle, and kidney. Elevated levels in lung. According to PubMed:9840943 highly expressed in testis, placenta, thymus and brain. In a lesser extent in small intestine and colon.
|
| Top Pathways |
Oocyte meiosis, Cell cycle, Measles, Viral carcinogenesis, PI3K-Akt signaling pathway
|
![Western Blot: Cyclin E2 Overexpression Lysate (Adult Normal) [NBL1-08878] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Cyclin E2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/4323_Cyclin%2520E2%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-08878-img0002.jpg)