NCOA2

Gene Symbol	NCOA2
Entrez Gene	10499
Alt Symbol	GRIP1, KAT13C, NCoA-2, SRC2, TIF2, bHLHe75
Species	Human
Gene Type	protein-coding
Description	nuclear receptor coactivator 2
Other Description	class E basic helix-loop-helix protein 75|glucocorticoid receptor-interacting protein-1|hTIF2|transcriptional intermediary factor 2
Swissprots	Q14CD2 Q15596
Accessions	CAH05317 EAW86963 Q15596 AK298528 BAG60730 AK308426 AW504723 BC047111 BC092442 AAH92442 BC114383 AAI14384 CK141607 EF374064 ABN46991 LN607830 CEF49517 X97674 CAA66263 XM_005251128 XP_005251185 XM_005251129 XP_005251186 XM_005251130 XP_005251187 XM_005251131 XP_005251188 XM_005251133 XP_005251190 XM_011517436 XP_011515738 XM_011517437 XP_011515739 XM_011517438 XP_011515740 XM_011517439 XP_011515741 XM_011517440 XP_011515742 XM_011517441 XP_011515743 NM_006540 NP_006531
Function	Transcriptional coactivator for steroid receptors and nuclear receptors. Coactivator of the steroid binding domain (AF- 2) but not of the modulating N-terminal domain (AF-1). Required with NCOA1 to control energy balance between white and brown adipose tissues. Critical regulator of glucose metabolism regulation, acts as RORA coactivator to specifically modulate G6PC expression. Involved in the positive regulation of the transcriptional activity of the glucocorticoid receptor NR3C1 by sumoylation enhancer RWDD3. Positively regulates the circadian clock by acting as a transcriptional coactivator for the CLOCK- ARNTL/BMAL1 heterodimer (By similarity). {ECO:0000250|UniProtKB:Q61026, ECO:0000269|PubMed:23508108, ECO:0000269|PubMed:9430642}.
Subcellular Location	Nucleus.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human KAT13C / NCOA2 protein fragment - ab161026 from Abcam Category Protein Source Wheat germ Species Human

KAT13C / NCOA2 peptide - ab4917 from Abcam Category Peptide

GRIP1 Antibody Blocking Peptide - LS-E31398 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

NCOA2 / TIF2 Antibody Blocking Peptide - LS-E13982 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human NCOA2 Protein - H00010499-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human GRIP1 Protein - H00023426-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

GRIP1 Blocking Peptide - 33R-6108 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

GRIP1 Blocking Peptide - 33R-8113 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

NCOA2 - H00010499-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

NCOA2 - H00010499-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

NCOA2 Control Peptide - AP10177CP-N from Acris Antibodies Category Peptide Prices $235.00 Sizes 250 µg

NCOA2 fusion protein - ag18077 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

NCOA2 fusion protein - ag16353 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human Nuclear receptor coactivator 2(NCOA2) ,partial - CSB-YP015540HU CSB-EP015540HU CSB-BP015540HU CSB-MP015540HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

SRC2 Blocking Peptide (OESA09490) - OESA09490 from Aviva Systems Biology Category Peptide Prices $245.00 Sizes 50 µg Species Human

GRIP1 Recombinant Protein Antigen - NBP1-86252PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

NCOA2-Blocking-Peptide-C-term - BP20987c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

NCOA2-Blocking-Peptide-Center - BP21855c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

NCOA2-Blocking-Peptide-C-Term - BP21793b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

GRIP1 Peptide, Human - M34GP06666H from Creative Peptides Category Peptide Source Synthetic. Species Human

NCOA2 Peptide, Human - M34GP10195H from Creative Peptides Category Peptide Source Synthetic. Species Human

NCOA2 Recombinant Protein Antigen - NBP2-55879PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Nuclear receptor coactivator 2 (NCOA2), partial, Recombinant Protein - MBS1471225 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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