HMOX2

Gene Symbol	HMOX2
Entrez Gene	3163
Alt Symbol	HO-2
Species	Human
Gene Type	protein-coding
Description	heme oxygenase 2
Other Description	heme oxygenase (decycling) 2
Swissprots	A8MT35 D3DUD5 O60605 P30519 I3L430
Accessions	AAV28730 EAW85299 EAW85300 P30519 AF051306 AAC05297 AK093388 BAG52702 AK222629 BAD96349 AK313660 BC002396 AAH02396 BE561721 BI225653 BM905872 BP329113 BP368949 BP369861 BT019788 AAV38591 CR456760 CAG33041 CR541839 CAG46638 D21243 BAA04789 DA141643 DA694137 DB184091 EU831457 ACE87144 EU831544 ACE86463 S34389 AAB22110 XM_011522473 XP_011520775 XM_011546746 XP_011545048 NM_001127204 NP_001120676 NM_001127205 NP_001120677 NM_001127206 NP_001120678 NM_001286267 NP_001273196 NM_001286268 NP_001273197 NM_001286269 NP_001273198 NM_001286270 NP_001273199 NM_001286271 NP_001273200 NM_002134 NP_002125
Function	Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Heme oxygenase 2 could be implicated in the production of carbon monoxide in brain where it could act as a neurotransmitter.
Subcellular Location	Microsome. Endoplasmic reticulum.
Top Pathways	Mineral absorption, Porphyrin and chlorophyll metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Heme Oxygenase 2 CRISPR/Cas9 KO Plasmid (h) - sc-402580 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Heme Oxygenase 2 HDR Plasmid (h) - sc-402580-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Heme Oxygenase 2 Double Nickase Plasmid (h) - sc-402580-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Heme Oxygenase 2 Double Nickase Plasmid (h2) - sc-402580-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Heme Oxygenase 2 CRISPR Activation Plasmid (h) - sc-402580-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Heme Oxygenase 2 CRISPR Activation Plasmid (h2) - sc-402580-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Heme Oxygenase 2 Lentiviral Activation Particles (h) - sc-402580-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Heme Oxygenase 2 Lentiviral Activation Particles (h2) - sc-402580-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Heme Oxygenase 2 siRNA (h) - sc-35556 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Heme Oxygenase 2 shRNA Plasmid (h) - sc-35556-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Heme Oxygenase 2 shRNA (h) Lentiviral Particles - sc-35556-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

HO-2/HMOX2 RNAi - H00003163-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU052711 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN10181 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10181 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR04977 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr04977

HMOX2 siRNA (Human) - CRH2159 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

HMOX2 - MBS8216185 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human HMOX2 (NM_002134.3) - SHH313537 from Creative biogene Category siRNA Species Reactivities Human

Human HMOX2 siRNA - orb262661 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

HMOX2 shRNA Plasmid (Human) - CHH2159 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

HMOX2 miRNA 3'UTR clone - MiUTR3H-01010 from Creative biogene Species Reactivities Human

HMOX2 miRNA 3'UTR clone - MiUTR3H-01011 from Creative biogene Species Reactivities Human

HMOX2 miRNA 3'UTR clone - MiUTR3H-01012 from Creative biogene Species Reactivities Human

HMOX2 miRNA 3'UTR clone - MiUTR3H-01013 from Creative biogene Species Reactivities Human

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