Gene Symbol | CDH3 |
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Entrez Gene | 1001 |
Alt Symbol | CDHP, HJMD, PCAD |
Species | Human |
Gene Type | protein-coding |
Description | cadherin 3, type 1, P-cadherin (placental) |
Other Description | cadherin-3|calcium-dependent adhesion protein, placental |
Swissprots | P22223 Q05DI6 B2R6F4 |
Accessions | CAA65093 CAJ34555 CCQ77686 CCQ77695 CCQ77704 CCQ77713 CCV20012 CDH48192 CDH61614 CDH61668 CDH61687 CDH88985 CDH92523 CDH92537 CDH92548 CDH92795 CDH92892 CDI44667 CDI44676 EAW83237 EAW83238 EAW83239 P22223 AI149268 AK225396 AK296968 BAG59512 AK312554 BAG35451 BC014462 AAH14462 BC041846 AAH41846 BQ945506 BU543746 CA489015 CA489338 CA489357 CN365479 EU832319 ACE87576 EU832404 ACE86889 X63629 CAA45177 XM_011522800 XP_011521102 NM_001793 NP_001784 |
Function | Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. |
Subcellular Location | Cell membrane; Single-pass type I membrane protein. |
Tissue Specificity | Expressed in some normal epithelial tissues and in some carcinoma cell lines. {ECO:0000269|PubMed:2702654}. |
Top Pathways | Cell adhesion molecules (CAMs) |
P-cadherin CRISPR/Cas9 KO Plasmid (h) - sc-400507 from Santa Cruz Biotechnology
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P-cadherin HDR Plasmid (h) - sc-400507-HDR from Santa Cruz Biotechnology
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P-cadherin Double Nickase Plasmid (h) - sc-400507-NIC from Santa Cruz Biotechnology
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P-cadherin Double Nickase Plasmid (h2) - sc-400507-NIC-2 from Santa Cruz Biotechnology
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P-cadherin CRISPR Activation Plasmid (h) - sc-400507-ACT from Santa Cruz Biotechnology
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P-cadherin CRISPR Activation Plasmid (h2) - sc-400507-ACT-2 from Santa Cruz Biotechnology
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P-cadherin Lentiviral Activation Particles (h) - sc-400507-LAC from Santa Cruz Biotechnology
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P-cadherin Lentiviral Activation Particles (h2) - sc-400507-LAC-2 from Santa Cruz Biotechnology
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P-cadherin siRNA (h) - sc-29420 from Santa Cruz Biotechnology
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P-cadherin shRNA Plasmid (h) - sc-29420-SH from Santa Cruz Biotechnology
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P-cadherin shRNA (h) Lentiviral Particles - sc-29420-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU024691 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5821 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5821 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05561 from Sigma-Aldrich
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CDH3 siRNA (Human) - CRH0715 from Cohesion Biosciences
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P-Cadherin RNAi - H00001001-R01 from Novus Biologicals
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CDH3 - MBS8222208 from MyBioSource
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shRNA set against Human CDH3 (NM_001793.4) - SHH260313 from Creative biogene
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CDH3 shRNA Plasmid (Human) - CHH0715 from Cohesion Biosciences
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CDH3 miRNA 3'UTR clone - MiUTR3H-00300 from Creative biogene
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