Gene Symbol | INSM2 |
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Entrez Gene | 84684 |
Alt Symbol | IA-6, IA6, mlt1 |
Species | Human |
Gene Type | protein-coding |
Description | insulinoma-associated 2 |
Other Description | insulinoma-associated protein 2|insulinoma-associated protein IA-6|zinc finger protein IA-6 |
Swissprots | Q96Q84 Q8N8K7 A1L432 Q96T92 J9Y024 |
Accessions | CCQ43774 EAW65872 Q96T92 AB037912 BAB69042 AF260323 AAK49393 AK096639 BAC04830 BC130377 AAI30378 BC130379 AAI30380 JX403968 AFS33107 NM_032594 NP_115983 |
Function | May function as a growth suppressor or tumor suppressor in liver cells and in certain neurons. {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. |
Tissue Specificity | Expressed in heart, liver, skeletal muscle, kidney and pancreas, and, to a lesser extent, in brain, lung and spleen. In the pancreas, expressed in islet cells, including insulin- and glucagon-producing alpha- and beta-cells, but not in acinar cells (at protein level). Detected in adrenal glands, particularly in the deeper layer of the cortex (at protein level). {ECO:0000269|PubMed:21343251}. |
INSM2 overexpression lysate - LY410009 from Acris Antibodies
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Panoply™ Human INSM2 Knockdown Stable Cell Line - CSC-DC007680 from Creative biogene
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