Gene Symbol | INSM2 |
---|---|
Entrez Gene | 84684 |
Alt Symbol | IA-6, IA6, mlt1 |
Species | Human |
Gene Type | protein-coding |
Description | insulinoma-associated 2 |
Other Description | insulinoma-associated protein 2|insulinoma-associated protein IA-6|zinc finger protein IA-6 |
Swissprots | Q96Q84 Q8N8K7 A1L432 Q96T92 J9Y024 |
Accessions | CCQ43774 EAW65872 Q96T92 AB037912 BAB69042 AF260323 AAK49393 AK096639 BAC04830 BC130377 AAI30378 BC130379 AAI30380 JX403968 AFS33107 NM_032594 NP_115983 |
Function | May function as a growth suppressor or tumor suppressor in liver cells and in certain neurons. {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. |
Tissue Specificity | Expressed in heart, liver, skeletal muscle, kidney and pancreas, and, to a lesser extent, in brain, lung and spleen. In the pancreas, expressed in islet cells, including insulin- and glucagon-producing alpha- and beta-cells, but not in acinar cells (at protein level). Detected in adrenal glands, particularly in the deeper layer of the cortex (at protein level). {ECO:0000269|PubMed:21343251}. |
INSM2 CRISPR/Cas9 KO Plasmid (h) - sc-410204 from Santa Cruz Biotechnology
|
||||||||
INSM2 HDR Plasmid (h) - sc-410204-HDR from Santa Cruz Biotechnology
|
||||||||
INSM2 Double Nickase Plasmid (h) - sc-410204-NIC from Santa Cruz Biotechnology
|
||||||||
INSM2 Double Nickase Plasmid (h2) - sc-410204-NIC-2 from Santa Cruz Biotechnology
|
||||||||
INSM2 CRISPR Activation Plasmid (h) - sc-410204-ACT from Santa Cruz Biotechnology
|
||||||||
INSM2 CRISPR Activation Plasmid (h2) - sc-410204-ACT-2 from Santa Cruz Biotechnology
|
||||||||
INSM2 Lentiviral Activation Particles (h) - sc-410204-LAC from Santa Cruz Biotechnology
|
||||||||
INSM2 Lentiviral Activation Particles (h2) - sc-410204-LAC-2 from Santa Cruz Biotechnology
|
||||||||
INSM2 siRNA (h) - sc-92409 from Santa Cruz Biotechnology
|
||||||||
INSM2 shRNA Plasmid (h) - sc-92409-SH from Santa Cruz Biotechnology
|
||||||||
INSM2 shRNA (h) Lentiviral Particles - sc-92409-V from Santa Cruz Biotechnology
|
||||||||
INSM2 RNAi - H00084684-R01 from Novus Biologicals
|
||||||||
MISSION® esiRNA - EHU000481 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN10707 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10707 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR08237 from Sigma-Aldrich
|
||||||||
INSM2 siRNA (Human) - CRJ3579 from Cohesion Biosciences
|
||||||||
INSM2 - MBS8234224 from MyBioSource
|
||||||||
shRNA set against Human INSM2 (NM_032594.3) - SHH319893 from Creative biogene
|
||||||||
shRNA set against Human INSM2(NM_032594.3) - SHL179274 from Creative biogene
|
||||||||
Human INSM2 siRNA - orb274080 from Biorbyt
|
||||||||
INSM2 shRNA Plasmid (Human) - CHJ3579 from Cohesion Biosciences
|
||||||||
INSM2 miRNA 3'UTR clone - MiUTR1H-04965 from Creative biogene
|