Gene Symbol | HSCB |
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Entrez Gene | 150274 |
Alt Symbol | DNAJC20, HSC20, JAC1, dJ366L4.2 |
Species | Human |
Gene Type | protein-coding |
Description | HscB mitochondrial iron-sulfur cluster co-chaperone |
Other Description | DnaJ (Hsp40) homolog, subfamily C, member 20|HscB iron-sulfur cluster co-chaperone homolog|J-type co-chaperone HSC20|dnaJ homolog subfamily C member 20|iron-sulfur cluster co-chaperone protein HscB, mitochondrial |
Swissprots | Q8IWL3 Q9BWS7 |
Accessions | EAW59758 EAW59759 EAW59760 Q8IWL3 AY191719 AAN85282 BC065569 AAH65569 CR456462 CAG30348 XM_005261359 XP_005261416 XM_005261360 XP_005261417 XM_005261361 XP_005261418 XR_937815 NM_172002 NP_741999 |
Function | Acts as a co-chaperone in iron-sulfur cluster assembly in mitochondria. {ECO:0000269|PubMed:20668094}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:20668094}. Mitochondrion {ECO:0000269|PubMed:20668094}. |
Tissue Specificity | Expressed in lung, brain, stomach, spleen, ovary, testis, liver, muscle and heart. {ECO:0000269|PubMed:12938016, ECO:0000269|PubMed:20668094}. |
HscB CRISPR/Cas9 KO Plasmid (h) - sc-409377 from Santa Cruz Biotechnology
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HscB HDR Plasmid (h) - sc-409377-HDR from Santa Cruz Biotechnology
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HscB Double Nickase Plasmid (h) - sc-409377-NIC from Santa Cruz Biotechnology
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HscB Double Nickase Plasmid (h2) - sc-409377-NIC-2 from Santa Cruz Biotechnology
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HscB CRISPR Activation Plasmid (h) - sc-409377-ACT from Santa Cruz Biotechnology
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HscB CRISPR Activation Plasmid (h2) - sc-409377-ACT-2 from Santa Cruz Biotechnology
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HscB Lentiviral Activation Particles (h) - sc-409377-LAC from Santa Cruz Biotechnology
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HscB Lentiviral Activation Particles (h2) - sc-409377-LAC-2 from Santa Cruz Biotechnology
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HscB siRNA (h) - sc-75306 from Santa Cruz Biotechnology
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HscB shRNA Plasmid (h) - sc-75306-SH from Santa Cruz Biotechnology
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HscB shRNA (h) Lentiviral Particles - sc-75306-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU044631 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10318 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10318 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02801 from Sigma-Aldrich
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HSCB siRNA (Human) - CRJ5647 from Cohesion Biosciences
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HSCB - MBS8231969 from MyBioSource
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shRNA set against Human HSCB (NM_172002.3) - SHH315093 from Creative biogene
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Human HSCB siRNA - orb276148 from Biorbyt
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HSCB shRNA Plasmid (Human) - CHJ5647 from Cohesion Biosciences
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HSCB miRNA 3'UTR clone - MiUTR1H-04710 from Creative biogene
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