| Gene Symbol |
Fut4
|
| Entrez Gene |
14345
|
| Alt Symbol |
AI451562, CD15, FAL, FucT-IV, LeX, SSEA-1, Ssea1
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
fucosyltransferase 4
|
| Other Description |
3-fucosyl-N-acetyl-lactosamine epitope|Lewis x|alpha (1,3) fucosyltransferase, myeloid specific|alpha 1,3-fucosyltransferase|alpha-(1,3)-fucosyltransferase 4|fuc-TIV|fucosyltransferase IV|galactoside 3-L-fucosyltransferase|stage-specific embryonic antigen 1
|
| Swissprots |
Q11127
|
| Accessions |
AAC52269 BAA09697 BAB68648 BAB68650 BAB68651 BAB68652 BAB68653 BAB68654 BAB68655 BAB68656 EDL25001 Q11127 AK041752 BAC31054 BC137588 AAI37589 D63379 BAA09696 NM_010242 NP_034372
|
| Function |
May catalyze alpha-1,3 glycosidic linkages involved in the expression of Lewis X/SSEA-1 and VIM-2 antigens.
|
| Subcellular Location |
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Membrane-bound form in trans cisternae of Golgi.
|
| Tissue Specificity |
Highest expression in stomach and colon. It is also expressed in the lung, testis, uterus, small intestine and to a lesser extent in spleen, and ovary. Present in trace amounts in brain, thymus, heart, smooth muscle, kidney and bone marrow. Not found in liver, salivary gland and pancreas.
|
| Top Pathways |
Other types of O-glycan biosynthesis, Glycosphingolipid biosynthesis - lacto and neolacto series
|