Gene Symbol | Fut4 |
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Entrez Gene | 14345 |
Alt Symbol | AI451562, CD15, FAL, FucT-IV, LeX, SSEA-1, Ssea1 |
Species | Mouse |
Gene Type | protein-coding |
Description | fucosyltransferase 4 |
Other Description | 3-fucosyl-N-acetyl-lactosamine epitope|Lewis x|alpha (1,3) fucosyltransferase, myeloid specific|alpha 1,3-fucosyltransferase|alpha-(1,3)-fucosyltransferase 4|fuc-TIV|fucosyltransferase IV|galactoside 3-L-fucosyltransferase|stage-specific embryonic antigen 1 |
Swissprots | Q11127 |
Accessions | AAC52269 BAA09697 BAB68648 BAB68650 BAB68651 BAB68652 BAB68653 BAB68654 BAB68655 BAB68656 EDL25001 Q11127 AK041752 BAC31054 BC137588 AAI37589 D63379 BAA09696 NM_010242 NP_034372 |
Function | May catalyze alpha-1,3 glycosidic linkages involved in the expression of Lewis X/SSEA-1 and VIM-2 antigens. |
Subcellular Location | Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Membrane-bound form in trans cisternae of Golgi. |
Tissue Specificity | Highest expression in stomach and colon. It is also expressed in the lung, testis, uterus, small intestine and to a lesser extent in spleen, and ovary. Present in trace amounts in brain, thymus, heart, smooth muscle, kidney and bone marrow. Not found in liver, salivary gland and pancreas. |
Top Pathways | Other types of O-glycan biosynthesis, Glycosphingolipid biosynthesis - lacto and neolacto series |
FucT-IV CRISPR/Cas9 KO Plasmid (m) - sc-420425 from Santa Cruz Biotechnology
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FucT-IV HDR Plasmid (m) - sc-420425-HDR from Santa Cruz Biotechnology
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FucT-IV Double Nickase Plasmid (m) - sc-420425-NIC from Santa Cruz Biotechnology
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FucT-IV Double Nickase Plasmid (m2) - sc-420425-NIC-2 from Santa Cruz Biotechnology
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FucT-IV CRISPR Activation Plasmid (m) - sc-420425-ACT from Santa Cruz Biotechnology
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FucT-IV CRISPR Activation Plasmid (m2) - sc-420425-ACT-2 from Santa Cruz Biotechnology
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FucT-IV Lentiviral Activation Particles (m) - sc-420425-LAC from Santa Cruz Biotechnology
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FucT-IV Lentiviral Activation Particles (m2) - sc-420425-LAC-2 from Santa Cruz Biotechnology
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FucT-IV siRNA (m) - sc-105376 from Santa Cruz Biotechnology
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FucT-IV shRNA Plasmid (m) - sc-105376-SH from Santa Cruz Biotechnology
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FucT-IV shRNA (m) Lentiviral Particles - sc-105376-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN31606 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND31606 from Sigma-Aldrich
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FUT4 siRNA (Mouse) - CRM1435 from Cohesion Biosciences
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FUT4 - MBS8226463 from MyBioSource
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shRNA set against Mouse FUT4 (NM_010242.3) - SHH297801 from Creative biogene
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FUT4 shRNA Plasmid (Mouse) - CHM1435 from Cohesion Biosciences
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FUT4 miRNA 3'UTR clone - MiUTR1M-04835 from Creative biogene
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