| Gene Symbol |
Pou2af1
|
| Entrez Gene |
18985
|
| Alt Symbol |
BOB.1, Bob-1, Bob1, OBF-1, OBF.1, OCA-B, OCAB
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
POU domain, class 2, associating factor 1
|
| Other Description |
B-cell-specific coactivator OBF-1|OCT-binding factor 1|POU domain class 2-associating factor 1
|
| Swissprots |
Q64693
|
| Accessions |
EDL25775 Q64693 AK088587 BAC40437 AK135080 BAE22412 BC058611 AAH58611 U43788 AAC52618 Z54283 CAA91058 NM_011136 NP_035266
|
| Function |
Transcriptional coactivator that specifically associates with either OCT1 or OCT2. It boosts the OCT1 mediated promoter activity and to a lesser extent, that of OCT2. It has no intrinsic DNA-binding activity. It recognizes the POU domains of OCT1 and OCT2. It is essential for the response of B-cells to antigens and required for the formation of germinal centers.
|
| Subcellular Location |
Nucleus.
|
| Tissue Specificity |
B-cell specific.
|