BAG6

Gene Symbol BAG6
Entrez Gene 7917
Alt Symbol BAG-6, BAT3, D6S52E, G3
Species Human
Gene Type protein-coding
Description BCL2-associated athanogene 6
Other Description BAG family molecular chaperone regulator 6|HLA-B associated transcript 3|HLA-B associated transcript-3|HLA-B-associated transcript 3|large proline-rich protein BAG6|large proline-rich protein BAT3|protein G3|protein Scythe|scythe
Swissprots A6NGY6 A6PWF7 Q5SQ41 A2ADJ7 Q5STC1 Q96SA6 Q5HYL9 P46379 Q5SRP9 Q5SQ35 Q5SQ36 A3KQ42 B4DZ12 Q5SQ37 B4E3V4 Q9BCN4 Q5STX3 E7EMZ4 O95874 Q5STX1 Q5SRP8 B0UX84 F8VXY4 A3KQ44
Accessions AAA35588 AAD18085 BAB63390 EAX03453 EAX03454 EAX03455 EAX03456 EAX03457 EAX03458 EAX03459 EAX03460 P46379 AK302695 BAG63924 AK304879 BAG65616 AU134255 BC003133 AAH03133 BF515863 BU628873 BX384328 BX647244 CAI46045 CX758454 DB454794 DB459208 DB492350 M33519 AAA35587 XM_006715192 XP_006715255 XM_006715198 XP_006715261 XM_006715201 XP_006715264 XM_006715203 XP_006715266 XM_006725509 XP_006725572 XM_006725515 XP_006725578 XM_006725518 XP_006725581 XM_006725520 XP_006725583 XM_006725725 XP_006725788 XM_006725729 XP_006725792 XM_006725731 XP_006725794 XM_006725734 XP_006725797 XM_006725736 XP_006725799 XM_006725835 XP_006725898 XM_006725839 XP_006725902 XM_006725841 XP_006725904 XM_006725844 XP_006725907 XM_006725846 XP_006725909 XM_006725923 XP_006725986 XM_006725927 XP_006725990 XM_006725929 XP_006725992 XM_006725932 XP_006725995 XM_006725934 XP_006725997 XM_006726025 XP_006726088 XM_006726031 XP_006726094 XM_006726034 XP_006726097 XM_006726036 XP_006726099 XM_006726113 XP_006726176 XM_006726119 XP_006726182 XM_006726122 XP_006726185 XM_006726124 XP_006726187 XM_011514891 XP_011513193 XM_011514892 XP_011513194 XM_011514893 XP_011513195 XM_011514894 XP_011513196 XM_011514895 XP_011513197 XM_011514896 XP_011513198 XM_011514897 XP_011513199 XM_011514898 XP_011513200 XM_011514899 XP_011513201 XM_011514900 XP_011513202 XM_011514901 XP_011513203 XM_011514902 XP_011513204 XM_011514903 XP_011513205 XM_011514904 XP_011513206 XM_011514905 XP_011513207 XM_011514906 XP_011513208 XM_011514907 XP_011513209 XM_011514908 XP_011513210 XM_011547291 XP_011545593 XM_011547292 XP_011545594 XM_011547293 XP_011545595 XM_011547294 XP_011545596 XM_011547295 XP_011545597 XM_011547296 XP_011545598 XM_011547297 XP_011545599 XM_011547298 XP_011545600 XM_011547299 XP_011545601 XM_011547300 XP_011545602 XM_011547301 XP_011545603 XM_011547302 XP_011545604 XM_011547303 XP_011545605 XM_011547304 XP_011545606 XM_011547305 XP_011545607 XM_011547306 XP_011545608 XM_011547307 XP_011545609 XM_011547308 XP_011545610 XM_011547309 XP_011545611 XM_011547310 XP_011545612 XM_011547693 XP_011545995 XM_011547694 XP_011545996 XM_011547695 XP_011545997 XM_011547696 XP_011545998 XM_011547697 XP_011545999 XM_011547698 XP_011546000 XM_011547699 XP_011546001 XM_011547700 XP_011546002 XM_011547701 XP_011546003 XM_011547702 XP_011546004 XM_011547703 XP_011546005 XM_011547704 XP_011546006 XM_011547705 XP_011546007 XM_011547706 XP_011546008 XM_011547707 XP_011546009 XM_011547708 XP_011546010 XM_011547709 XP_011546011 XM_011547710 XP_011546012 XM_011547912 XP_011546214 XM_011547913 XP_011546215 XM_011547914 XP_011546216 XM_011547915 XP_011546217 XM_011547916 XP_011546218 XM_011547917 XP_011546219 XM_011547918 XP_011546220 XM_011547919 XP_011546221 XM_011547920 XP_011546222 XM_011547921 XP_011546223 XM_011547922 XP_011546224 XM_011547923 XP_011546225 XM_011547924 XP_011546226 XM_011547925 XP_011546227 XM_011547926 XP_011546228 XM_011547927 XP_011546229 XM_011547928 XP_011546230 XM_011547929 XP_011546231 XM_011548081 XP_011546383 XM_011548082 XP_011546384 XM_011548083 XP_011546385 XM_011548084 XP_011546386 XM_011548085 XP_011546387 XM_011548086 XP_011546388 XM_011548087 XP_011546389 XM_011548088 XP_011546390 XM_011548089 XP_011546391 XM_011548090 XP_011546392 XM_011548091 XP_011546393 XM_011548092 XP_011546394 XM_011548093 XP_011546395 XM_011548094 XP_011546396 XM_011548095 XP_011546397 XM_011548096 XP_011546398 XM_011548097 XP_011546399 XM_011548277 XP_011546579 XM_011548278 XP_011546580 XM_011548279 XP_011546581 XM_011548280 XP_011546582 XM_011548281 XP_011546583 XM_011548282 XP_011546584 XM_011548283 XP_011546585 XM_011548284 XP_011546586 XM_011548285 XP_011546587 XM_011548286 XP_011546588 XM_011548287 XP_011546589 XM_011548288 XP_011546590 XM_011548289 XP_011546591 XM_011548290 XP_011546592 XM_011548291 XP_011546593 XM_011548292 XP_011546594 XM_011548293 XP_011546595 XM_011548294 XP_011546596 XM_011548295 XP_011546597 XM_011548296 XP_011546598 XM_011548465 XP_011546767 XM_011548466 XP_011546768 XM_011548467 XP_011546769 XM_011548468 XP_011546770 XM_011548469 XP_011546771 XM_011548470 XP_011546772 XM_011548471 XP_011546773 XM_011548472 XP_011546774 XM_011548473 XP_011546775 XM_011548474 XP_011546776 XM_011548475 XP_011546777 XM_011548476 XP_011546778 XM_011548477 XP_011546779 XM_011548478 XP_011546780 XM_011548479 XP_011546781 XM_011548480 XP_011546782 XM_011548481 XP_011546783 XM_011548482 XP_011546784 XM_011548483 XP_011546785 XM_011548484 XP_011546786 NM_001098534 NP_001092004 NM_001199697 NP_001186626 NM_001199698 NP_001186627 NM_004639 NP_004630 NM_080702 NP_542433 NM_080703 NP_542434
Function Can be released from tumor and dendritic cells in membrane vesicles or exosomes, and engage NCR3 thereby promoting natural killer cells (NK) activation and cytotoxicity. {ECO:0000269|PubMed:18055229, ECO:0000269|PubMed:18852879}.
Subcellular Location Cytoplasm, cytosol. Nucleus. Note=The C- terminal fragment generated by caspase-3 is cytoplasmic. Also found in extracellular vesicular exosomes in some tumor cells.

BAG6 Antibody - 8523 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell lines using BAG6 Antibody.

BAG-6 (D-1) - sc-365928 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
BAG-6 (D-1): sc-365928. Western blot analysis of BAG-6 expression in NTERA-2 cl.D1 (A) and U-87 MG (B) whole cell lysates.

BAG-6 (P-18) - sc-82531 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
BAG-6 (P-18): sc-82531. Western blot analysis of BAG-6 expression in MCF7 (A), HEK293 (B) and Hep G2 (C) whole cell lysates.

BAG-6 (H-300) - sc-98519 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
BAG-6 (H-300): sc-98519. Immunoperoxidase staining of formalin fixed, paraffin-embedded human salivary gland tissue showing nuclear and cytoplasmic staining of glandular cells.

BAG-6 (C-17) - sc-82528 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
BAG-6 (C-17): sc-82528. Western blot analysis of BAG-6 expression in MCF7 (A) and HEK293 (B) whole cell lysates.

Anti-BAT3 antibody - ab88292 from Abcam

Prices $385.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-BAT3 antibody (ab88292) at 1 µg/ml + A-431 cell lysate with BAT3 expression at 50 µgSecondaryGoat Anti-Mouse IgG at 1/2500 dilution

Anti-BAT3 antibody - ab37751 from Abcam

Prices $376.00
Sizes 50 µg
Host Chicken
Clonality Polyclonal

Anti-BAT3 antibody - ab180621 from Abcam

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human spleen tissue labeling BAT3 with ab180621 at 3.8 µg/ml.

Anti-BAT3 antibody [EPR9223] - ab137076 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR9223
Overlay histogram showing Hela cells stained with ab137076 (red line). The cells were fixed with 80% methanol (5 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab137076, 1/1000 dilution) for 30 min at 22°C. The secondary antibody used was Alexa Fluor® 488 goat anti-rabbit IgG (H&L) (ab150077) at 1/2000 dilution for 30 min at 22°C. Isotype control antibody (black line) was rabbit IgG (monoclonal) (0.1μg/1x106 cells) used under the same conditions. Unlabelled sample (blue line) was also used as a control. Acquisition of >5,000 events were collected using a 20mW Argon ion laser (488nm) and 525/30 bandpass filter. This antibody gave a positive signal in HeLa cells fixed with 4% paraformaldehyde (10 min)/permeabilized with 0.1% PBS-Tween for 20 min used under the same conditions.

Anti-BAT3 antibody - C-terminal - ab167079 from Abcam

Prices $376.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human testis tissue labeling BAT3 with ab167079 at 10 µg/ml.

Anti-BAG6 / G3 / Scythe Antibody (clone 2B9) - LS-C198511 from LifeSpan Bioscience

Prices $355.00
Sizes 200 µl
Host Mouse
Clonality Monoclonal
Clone 2B9

Anti-BAG6 / G3 / Scythe Antibody (aa1072-1099, APC) - LS-C221514 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BAG6 / G3 / Scythe Antibody (aa1072-1099, AP) - LS-C221513 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BAG6 / G3 / Scythe Antibody (aa1072-1099, Biotin) - LS-C221515 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BAG6 / G3 / Scythe Antibody (aa1072-1099, FITC) - LS-C221516 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BAG6 / G3 / Scythe Antibody (aa1072-1099, Azide-free, HRP) - LS-C221517 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BAG6 / G3 / Scythe Antibody (aa1072-1099, PE) - LS-C221519 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BAG6 / G3 / Scythe Antibody (N-Terminus) IHC-plus™ - LS-B8133 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Anti-BAG6 / G3 / Scythe antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8133 dilution 1:100.

Anti-BAG6 / G3 / Scythe Antibody (aa200-250) - LS-C288796 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-BAG6 / G3 / Scythe Antibody (aa1082-1132) - LS-C288800 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-BAG6 / G3 / Scythe Antibody - LS-C306500 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-BAG6 / G3 / Scythe Antibody - LS-C309587 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-BAG6 / G3 / Scythe Antibody (aa1072-1099) - LS-C156748 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
BAT3 Antibody western blot of A2058 cell line lysates (35 ug/lane). The BAT3 antibody detected the BAT3 protein (arrow).

Anti-BAG6 / G3 / Scythe Antibody (aa1071-1099) - LS-C319781 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BAG6 / G3 / Scythe Antibody (C-Terminus) IHC-plus™ - LS-B8487 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-BAG6 / G3 / Scythe antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8487 dilution 5-10 ug/ml.
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