| Gene Symbol | ANO5 |
|---|---|
| Entrez Gene | 203859 |
| Alt Symbol | GDD1, LGMD2L, TMEM16E |
| Species | Human |
| Gene Type | protein-coding |
| Description | anoctamin 5 |
| Other Description | anoctamin-5|gnathodiaphyseal dysplasia 1 protein|integral membrane protein GDD1|transmembrane protein 16E |
| Swissprots | Q75V66 |
| Accessions | EAW68325 Q75V66 AB125267 BAD17859 AK092680 AK125046 AL832374 AL833271 BC156325 AAI56326 BC172489 AAI72489 BU742779 N89918 XM_005252820 XP_005252877 XM_005252821 XP_005252878 XM_005252822 XP_005252879 XM_005252823 XP_005252880 XM_011519949 XP_011518251 NM_001142649 NP_001136121 NM_213599 NP_998764 |
| Function | Does not exhibit calcium-activated chloride channel (CaCC) activity. |
| Subcellular Location | Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell membrane. Note=Colocalized with CALR/calreticulin. Shows an intracellular localization according to PubMed:22075693. |
| Tissue Specificity | Highly expressed in brain, heart, kidney, lung, and skeletal muscle. Weakly expressed in bone marrow, fetal liver, placenta, spleen, thymus, osteoblasts and periodontal ligament cells. {ECO:0000269|PubMed:15067359, ECO:0000269|PubMed:15124103}. |
Panoply™ Human ANO5 Knockdown Stable Cell Line - CSC-DC000680 from Creative biogene
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