Gene Symbol | ANO5 |
---|---|
Entrez Gene | 203859 |
Alt Symbol | GDD1, LGMD2L, TMEM16E |
Species | Human |
Gene Type | protein-coding |
Description | anoctamin 5 |
Other Description | anoctamin-5|gnathodiaphyseal dysplasia 1 protein|integral membrane protein GDD1|transmembrane protein 16E |
Swissprots | Q75V66 |
Accessions | EAW68325 Q75V66 AB125267 BAD17859 AK092680 AK125046 AL832374 AL833271 BC156325 AAI56326 BC172489 AAI72489 BU742779 N89918 XM_005252820 XP_005252877 XM_005252821 XP_005252878 XM_005252822 XP_005252879 XM_005252823 XP_005252880 XM_011519949 XP_011518251 NM_001142649 NP_001136121 NM_213599 NP_998764 |
Function | Does not exhibit calcium-activated chloride channel (CaCC) activity. |
Subcellular Location | Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell membrane. Note=Colocalized with CALR/calreticulin. Shows an intracellular localization according to PubMed:22075693. |
Tissue Specificity | Highly expressed in brain, heart, kidney, lung, and skeletal muscle. Weakly expressed in bone marrow, fetal liver, placenta, spleen, thymus, osteoblasts and periodontal ligament cells. {ECO:0000269|PubMed:15067359, ECO:0000269|PubMed:15124103}. |
TMEM16E CRISPR/Cas9 KO Plasmid (h) - sc-405649 from Santa Cruz Biotechnology
|
||||||||
TMEM16E HDR Plasmid (h) - sc-405649-HDR from Santa Cruz Biotechnology
|
||||||||
TMEM16E Double Nickase Plasmid (h) - sc-405649-NIC from Santa Cruz Biotechnology
|
||||||||
TMEM16E Double Nickase Plasmid (h2) - sc-405649-NIC-2 from Santa Cruz Biotechnology
|
||||||||
TMEM16E CRISPR Activation Plasmid (h) - sc-405649-ACT from Santa Cruz Biotechnology
|
||||||||
TMEM16E CRISPR Activation Plasmid (h2) - sc-405649-ACT-2 from Santa Cruz Biotechnology
|
||||||||
TMEM16E Lentiviral Activation Particles (h) - sc-405649-LAC from Santa Cruz Biotechnology
|
||||||||
TMEM16E Lentiviral Activation Particles (h2) - sc-405649-LAC-2 from Santa Cruz Biotechnology
|
||||||||
TMEM16E siRNA (h) - sc-97047 from Santa Cruz Biotechnology
|
||||||||
TMEM16E shRNA Plasmid (h) - sc-97047-SH from Santa Cruz Biotechnology
|
||||||||
TMEM16E shRNA (h) Lentiviral Particles - sc-97047-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU008651 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN3245 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3245 from Sigma-Aldrich
|
||||||||
ANO5 siRNA (Human) - CRJ6351 from Cohesion Biosciences
|
||||||||
ANO5 - MBS828703 from MyBioSource
|
||||||||
shRNA set against Human ANO5 (NM_213599.2) - SHH237346 from Creative biogene
|
||||||||
Human ANO5 siRNA - orb276852 from Biorbyt
|
||||||||
ANO5 shRNA Plasmid (Human) - CHJ6351 from Cohesion Biosciences
|
||||||||
ANO5 miRNA 3'UTR clone - MiUTR4H-TG00368 from Creative biogene
|