| Gene Symbol |
ABCG5
|
| Entrez Gene |
64240
|
| Alt Symbol |
STSL
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ATP-binding cassette, sub-family G (WHITE), member 5
|
| Other Description |
ATP-binding cassette sub-family G member 5|ATP-binding cassette, subfamily G, member 5|sterolin 1|sterolin-1
|
| Swissprots |
Q96QZ2 Q96QZ3 Q2T9G2 Q9H222
|
| Accessions |
AAK85387 AAK85388 AAY14703 AAY24010 EAX00286 EAX00287 EAX00288 Q9H222 AF312715 AAG53099 AF320293 AAG40003 AK091997 BC111541 AAI11542 BC111542 BC172287 AAI72287 XM_005264480 XP_005264537 XM_006712073 XP_006712136 XM_006712074 XP_006712137 XM_011533024 XP_011531326 XM_011533025 XP_011531327 XM_011533026 XP_011531328 XM_011533027 XP_011531329 XM_011533028 XP_011531330 NM_022436 NP_071881
|
| Function |
Transporter that appears to play an indispensable role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile.
|
| Subcellular Location |
Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
|
| Tissue Specificity |
Strongly expressed in the liver, lower levels in the small intestine and colon.
|
| Top Pathways |
ABC transporters, Bile secretion, Fat digestion and absorption
|