Gene Symbol | ABCG5 |
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Entrez Gene | 64240 |
Alt Symbol | STSL |
Species | Human |
Gene Type | protein-coding |
Description | ATP-binding cassette, sub-family G (WHITE), member 5 |
Other Description | ATP-binding cassette sub-family G member 5|ATP-binding cassette, subfamily G, member 5|sterolin 1|sterolin-1 |
Swissprots | Q96QZ2 Q96QZ3 Q2T9G2 Q9H222 |
Accessions | AAK85387 AAK85388 AAY14703 AAY24010 EAX00286 EAX00287 EAX00288 Q9H222 AF312715 AAG53099 AF320293 AAG40003 AK091997 BC111541 AAI11542 BC111542 BC172287 AAI72287 XM_005264480 XP_005264537 XM_006712073 XP_006712136 XM_006712074 XP_006712137 XM_011533024 XP_011531326 XM_011533025 XP_011531327 XM_011533026 XP_011531328 XM_011533027 XP_011531329 XM_011533028 XP_011531330 NM_022436 NP_071881 |
Function | Transporter that appears to play an indispensable role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile. |
Subcellular Location | Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. |
Tissue Specificity | Strongly expressed in the liver, lower levels in the small intestine and colon. |
Top Pathways | ABC transporters, Bile secretion, Fat digestion and absorption |
ABCG5 CRISPR/Cas9 KO Plasmid (h) - sc-402729 from Santa Cruz Biotechnology
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ABCG5 HDR Plasmid (h) - sc-402729-HDR from Santa Cruz Biotechnology
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ABCG5 Double Nickase Plasmid (h) - sc-402729-NIC from Santa Cruz Biotechnology
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ABCG5 Double Nickase Plasmid (h2) - sc-402729-NIC-2 from Santa Cruz Biotechnology
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ABCG5 CRISPR Activation Plasmid (h) - sc-402729-ACT from Santa Cruz Biotechnology
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ABCG5 CRISPR Activation Plasmid (h2) - sc-402729-ACT-2 from Santa Cruz Biotechnology
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ABCG5 Lentiviral Activation Particles (h) - sc-402729-LAC from Santa Cruz Biotechnology
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ABCG5 Lentiviral Activation Particles (h2) - sc-402729-LAC-2 from Santa Cruz Biotechnology
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ABCG5 siRNA (h) - sc-41152 from Santa Cruz Biotechnology
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ABCG5 shRNA Plasmid (h) - sc-41152-SH from Santa Cruz Biotechnology
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ABCG5 shRNA (h) Lentiviral Particles - sc-41152-V from Santa Cruz Biotechnology
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ABCG5 RNAi - H00064240-R01 from Novus Biologicals
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MISSION® esiRNA - EHU005871 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2650 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2650 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05099 from Sigma-Aldrich
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ABCG5 siRNA (Human) - CRJ1973 from Cohesion Biosciences
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ABCG5 - MBS8219797 from MyBioSource
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shRNA set against Human Abcg5 (NM_022436.2) - SHH229350 from Creative biogene
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shRNA set against Human ABCG5(NM_022436.2) - SHG025291 from Creative biogene
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Human ABCG5 siRNA - orb272474 from Biorbyt
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ABCG5 shRNA Plasmid (Human) - CHJ1973 from Cohesion Biosciences
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ABCG5 miRNA 3'UTR clone - MiUTR1H-00060 from Creative biogene
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