| Gene Symbol |
PC
|
| Entrez Gene |
338471
|
| Alt Symbol |
-
|
| Species |
Bovine
|
| Gene Type |
protein-coding
|
| Description |
pyruvate carboxylase
|
| Other Description |
PCB|pyruvate carboxylase, mitochondrial|pyruvic carboxylase
|
| Swissprots |
Q866R1 Q29RK2
|
| Accessions |
DAA13691 Q29RK2 AY185595 AAO27903 AY185596 AAO27904 AY185597 AAO27905 AY185598 AAO27906 AY185599 AAO27907 AY185600 AAO27908 BC114135 AAI14136 XM_005226987 XP_005227044 XM_005226988 XP_005227045 XM_005226989 XP_005227046 XM_005226990 XP_005227047 XM_005226991 XP_005227048 XM_005226992 XP_005227049 XM_005226993 XP_005227050 XM_005226994 XP_005227051 XM_010821049 XP_010819351 XM_010821050 XP_010819352 NM_177946 NP_808815
|
| Function |
Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. Catalyzes in a tissue specific manner, the initial reactions of glucose (liver, kidney) and lipid (adipose tissue, liver, brain) synthesis from pyruvate (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Mitochondrion matrix {ECO:0000250}.
|
| Top Pathways |
Citrate cycle (TCA cycle), Pyruvate metabolism, Biosynthesis of amino acids, Carbon metabolism
|