| Gene Symbol |
TIMM22
|
| Entrez Gene |
29928
|
| Alt Symbol |
TEX4, TIM22
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
translocase of inner mitochondrial membrane 22 homolog (yeast)
|
| Other Description |
mitochondrial import inner membrane translocase subunit Tim22|putative membrane protein|testis-expressed sequence 4
|
| Swissprots |
Q9NWI8 Q9Y584
|
| Accessions |
EAW90637 EAW90638 Q9Y584 AF155330 AAD40106 AK000830 BAA91392 AK225453 BC002324 AAH02324 NM_013337 NP_037469
|
| Function |
Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Mitochondrion inner membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
|